Structure of PDB 6zmi Chain Lo Binding Site BS02

Receptor Information
>6zmi Chain Lo (length=105) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQ
TKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKG
QVIQF
Ligand information
>6zmi Chain CC (length=75) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uccgauauagcguaacggcuaucacaucacgcuuucaccguggagaccgg
gguucgacuccccguaucggagcca
<<<<<<<..<.<..........>.>.<<<<<.......>>>>>....<<<
<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
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PDB6zmi Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Resolution2.6 Å
Binding residue
(original residue number in PDB)
K38 Y41 K53 P54
Binding residue
(residue number reindexed from 1)
K37 Y40 K52 P53
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005886 plasma membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:6zmi, PDBe:6zmi, PDBj:6zmi
PDBsum6zmi
PubMed32680882
UniProtP83881|RL36A_HUMAN Large ribosomal subunit protein eL42 (Gene Name=RPL36A)

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