Structure of PDB 7nrd Chain Ll Binding Site BS02

Receptor Information
>7nrd Chain Ll (length=81) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKGTPSFGKRHNKSHTLCNRCGRRSFHVQKKTCSSCGYPAAKTRSYNWGA
KAKRRHTTGTGRMRYLKHVSRRFKNGFQTGS
Ligand information
>7nrd Chain LC (length=158) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaacuuucaacaacggaucucuugguucucgcaucgaugaagaacgcagc
gaaaugcgauacguaaugugaauugcagaauuccgugaaucaucgaaucu
uugaacgcacauugcgccccuugguauuccagggggcaugccuguuugag
cgucauuu
Receptor-Ligand Complex Structure
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PDB7nrd Structure of Gcn1 bound to stalled and colliding 80S ribosomes.
Resolution4.36 Å
Binding residue
(original residue number in PDB)		R21 G23 F27 V29 K32 T59 G60 T61 G62 R63 M64 R65 Y66 L67 K68 V70 R72 R73 F74 K75 N76 Q79 T80 G81 S82
Binding residue
(residue number reindexed from 1)		R20 G22 F26 V28 K31 T58 G59 T60 G61 R62 M63 R64 Y65 L66 K67 V69 R71 R72 F73 K74 N75 Q78 T79 G80 S81
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0008270 zinc ion binding
GO:0019843 rRNA binding
GO:0046872 metal ion binding
Biological Process
GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0030687 preribosome, large subunit precursor
GO:0044391 ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7nrd, PDBe:7nrd, PDBj:7nrd
PDBsum7nrd
PubMed33790014
UniProtP49166|RL37A_YEAST Large ribosomal subunit protein eL37A (Gene Name=RPL37A)

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