Structure of PDB 8pv5 Chain Lj Binding Site BS02

Receptor Information

>8pv5 Chain Lj (length=88) Species: 759272 (Thermochaetoides thermophila DSM 1495)

TKGTSSFGKRHNKTHGLCRRCGRRSLHNQKKVCASCGYPAAKTRKYNWSE
KAKRRKVTGTGRMRYLSTVPRRFKNGFRTGVPKGARGP

Ligand information

>8pv5 Chain C2 (length=152)

aaacuuucaacaacggaucucuugguucuggcaucgaugaagaacgcagc
gaaaugcgauaaguaaugugaauugcagaagugaaucaucgaaucuuuga
acgcacauugcgcccgccgguauuccggcgggcaugccuguucgagcguc
au

.........................................<<<<<<<((
....>>>>.....<.<<<<.....))........>.>>>..>...>>>..
..<<.....>><<<<<<<<<....>>>>>>>>>.................
..

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8pv5 Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
• Resolution: 2.86 Å
• Binding residue (original residue number in PDB): R20 R21 C22 G23 N29 Y39 T59 G62 R63 M64 R65 Y66 L67 R72 F74 K75 N76 R79 T80 G81 P83 R87
• Binding residue (residue number reindexed from 1): R19 R20 C21 G22 N28 Y38 T58 G61 R62 M63 R64 Y65 L66 R71 F73 K74 N75 R78 T79 G80 P82 R86

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8pv5, PDBe:8pv5, PDBj:8pv5
• PDBsum: 8pv5
• PubMed: 37921038
• UniProt: G0S101