Structure of PDB 8i9y Chain Lj Binding Site BS02

Receptor Information

>8i9y Chain Lj (length=74) Species: 759272 (Thermochaetoides thermophila DSM 1495)

KTHGLCRRCGRRSLHNQKKVCASCGYPAAKTRKYNWSEKAKRRKVTGTGR
MRYLSTVPRRFKNGFRTGVPKGAR

Ligand information

>8i9y Chain C2 (length=256)

aaacuuucaacaacggaucucuugguucuggcaucgaugaagaacgcagc
gaaaugcgauaaguaaugugaauugcagaauuccgugaaucaucgaaucu
uugaacgcacauugcgcccgccgguauuccggcgggcaugccuguucgag
cgucauuucaaccaucaagcccugggcuuguguuggggacccgcggcugc
ucgcgggcccugaaaagcaguggcgggcucgcuggcgggugccagccgua
aaaccc

.........................................<<<<<<<((
....>>>>.....<.<<<<.....))............>.>>>..>...>
>>....<<.....>><<<<<<<<<....>>>>>>>>>.............
...............<<<<<<...>>>>>>....<<<<.<<<<<<<....
>>>>>>>>>>>.........<<<<<<<<<<<<..>>>>>>.>>.>>>>..
......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8i9y Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
• Resolution: 3.1 Å
• Binding residue (original residue number in PDB): L18 R20 R21 L27 Y39 T59 G62 R63 M64 R65 Y66 L67 R72 F74 K75 N76 R79 G81 P83 R87
• Binding residue (residue number reindexed from 1): L5 R7 R8 L14 Y26 T46 G49 R50 M51 R52 Y53 L54 R59 F61 K62 N63 R66 G68 P70 R74

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8i9y, PDBe:8i9y, PDBj:8i9y
• PDBsum: 8i9y
• PubMed: 37129998
• UniProt: G0S101