Structure of PDB 8i9x Chain Lj Binding Site BS02

Receptor Information

>8i9x Chain Lj (length=74) Species: 759272 (Thermochaetoides thermophila DSM 1495)

KTHGLCRRCGRRSLHNQKKVCASCGYPAAKTRKYNWSEKAKRRKVTGTGR
MRYLSTVPRRFKNGFRTGVPKGAR

Ligand information

>8i9x Chain C2 (length=256)

aaacuuucaacaacggaucucuugguucuggcaucgaugaagaacgcagc
gaaaugcgauaaguaaugugaauugcagaauuccgugaaucaucgaaucu
uugaacgcacauugcgcccgccgguauuccggcgggcaugccuguucgag
cgucauuucaaccaucaagcccugggcuuguguuggggacccgcggcugc
ucgcgggcccugaaaagcaguggcgggcucgcuggcgggugccagccgua
aaaccc

.........................................<<<<<<<<<
....>>>>.....<.<<<......>>..............>>>..>...>
>>....<<.....>><<<<<<<<<....>>>>>>>>>.............
...............<<<<<<...>>>>>>....<<<<.<<<<<<<....
>>>>>>>>>>>.........<<<<<<<<<<<<..>>>>>>.>>.>>>>..
......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8i9x Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
• Resolution: 2.8 Å
• Binding residue (original residue number in PDB): L18 R20 R21 L27 G62 R63 M64 R65 Y66 L67 R72 F74 N76 R79 T80 G81 P83 A86 R87
• Binding residue (residue number reindexed from 1): L5 R7 R8 L14 G49 R50 M51 R52 Y53 L54 R59 F61 N63 R66 T67 G68 P70 A73 R74

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8i9x, PDBe:8i9x, PDBj:8i9x
• PDBsum: 8i9x
• PubMed: 37129998
• UniProt: G0S101