Structure of PDB 7mq9 Chain LZ Binding Site BS02

Receptor Information
>7mq9 Chain LZ (length=183) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VRKLKFHEQKLLKQVDFLNWEVTDHNLHELRVLRRYRLQRREDYTRYNQL
SRAVRELARRLRDLPERDQFRVRASAALLDKLYALGLVPTRGSLELCDFV
TASSFCRRRLPTVLLKLRMAQHLQAAVAFVEQGHVRVGPDVVTDPAFLVT
RSMEDFVTWVDSSKIKRHVLEYNEERDDFDLEA
Ligand information
>7mq9 Chain L2 (length=215) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gacuauacuuucagggaucauuucuauaguguguuacuagagaaguuucu
cugaacguguagagcaccgaaaaccacgaggaagagagguagcguuuucu
ccugagcgugaagccggcuuucuggcguugcuuggcugcaacugccguca
gccauugaugaucguucuucucuccguauuggggagugagagggagagaa
cgcggucugaguggu
..................................................
.......................<<<<.....<<.......<<<<<<<<<
<<<....<.......<<<<....<<<.<<<<......>>>>..>>>...>
>>>.........>..<<<<<<<<<<.....>>>>>>.>>>>>>>>>>>>>
>>>...>>..>>>>.
Receptor-Ligand Complex Structure
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PDB7mq9 Nucleolar maturation of the human small subunit processome.
Resolution3.87 Å
Binding residue
(original residue number in PDB)
F7 K11 L12 L13 K14 Q133 K165 H169
Binding residue
(residue number reindexed from 1)
F6 K10 L11 L12 K13 Q132 K164 H168
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0030515 snoRNA binding
Biological Process
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030684 preribosome
GO:0032040 small-subunit processome
GO:0034457 Mpp10 complex
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7mq9, PDBe:7mq9, PDBj:7mq9
PDBsum7mq9
PubMed34516797
UniProtQ9NV31|IMP3_HUMAN U3 small nucleolar ribonucleoprotein protein IMP3 (Gene Name=IMP3)

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