Structure of PDB 8oj8 Chain LX Binding Site BS02

Receptor Information
>8oj8 Chain LX (length=118) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMK
KIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYV
RLAPDYDALDVANKIGII
Ligand information
>8oj8 Chain 8 (length=148) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacaugaucaucgacacuucga
acgcacuugcggccccgggcccggggcuacgccugucugagcgucgcu
.........................................<<<<<<<<<
....>>>>.....<.<<<......>>..........>>>..>...>>>..
..<<....>><<<<<<<<<>>>>>>>>>....................
Receptor-Ligand Complex Structure
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PDB8oj8 UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER
Resolution3.3 Å
Binding residue
(original residue number in PDB)
P49 T51 L52 R56 P66 R67 R68 K70 H107 Q108
Binding residue
(residue number reindexed from 1)
P11 T13 L14 R18 P28 R29 R30 K32 H69 Q70
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0045296 cadherin binding
GO:1904841 TORC2 complex binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0070062 extracellular exosome
GO:1990904 ribonucleoprotein complex

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Biological Process

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Cellular Component
External links
PDB RCSB:8oj8, PDBe:8oj8, PDBj:8oj8
PDBsum8oj8
PubMed38383785
UniProtP62750|RL23A_HUMAN Large ribosomal subunit protein uL23 (Gene Name=RPL23A)

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