Structure of PDB 7mq8 Chain LS Binding Site BS02

Receptor Information
>7mq8 Chain LS (length=453) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVAAAEEERRLRQRNRLRLEEDKPAVERCLEELVFGDVENDEDALLRRLR
KKPVWVDEEDEDEEMVDMMNNRFRKDMMKNASESKLSKDNLKKRLKEEFQ
HAMGGVPAWAEDDLLQRTGNFISTSTSLPRGILKMKNCQHANAERPTVAR
ISSVQFHPGAQIVMVAGLDNAVSLFQVDGKTNPKIQSIYLERFPIFKACF
SANGEEVLATSTHSKVLYVYDMLAGKLIPVHQVRGLKEKIVRSFEVSPDG
SFLLINGIAGYLHLLAMKTKELIGSMKINGRVAASTFSSDSKKVYASSGD
GEVYVWDVNSRKCLNRFVDEGSLYGLSIATSRNGQYVACGSNCGVVNIYN
QDSCLQETNPKPIKAIMNLVTGVTSLTFNPTTEILAIASEKMKEAVRLVH
LPSCTVFSNFPVIKNKNISHVHTMDFSPRSGYFALGNEKGKALMYRLHHY
SDF
Ligand information
>7mq8 Chain L2 (length=215) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gacuauacuuucagggaucauuucuauaguguguuacuagagaaguuucu
cugaacguguagagcaccgaaaaccacgaggaagagagguagcguuuucu
ccugagcgugaagccggcuuucuggcguugcuuggcugcaacugccguca
gccauugaugaucguucuucucuccguauuggggagugagagggagagaa
cgcggucugaguggu
..................................................
.......................<<<<.....<<.......<<<<<<<<<
<<<....<.......<<<<....<<<<<<<<......>>>>>.>>>...>
>>>.........>..<<<<<<<<<<.....>>>>>>.>>>>>>>>>>>>>
>>>...>>..>>>>.
Receptor-Ligand Complex Structure
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PDB7mq8 Nucleolar maturation of the human small subunit processome.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		N471 R500 S511
Binding residue
(residue number reindexed from 1)		N368 R397 S408
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0006364 rRNA processing
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0031965 nuclear membrane
GO:0032040 small-subunit processome
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7mq8, PDBe:7mq8, PDBj:7mq8
PDBsum7mq8
PubMed34516797
UniProtQ9Y5J1|UTP18_HUMAN U3 small nucleolar RNA-associated protein 18 homolog (Gene Name=UTP18)

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