Structure of PDB 7cpv Chain LS Binding Site BS02

Receptor Information

>7cpv Chain LS (length=175) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQL
KKMKKSSGEIVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDLT
TAGAVTQCYRDMGARHRARAHSIQIMKVEEIAAGKCRRPAVKQFHDSKIK
FPLPHRVLRRQHKPRFTTKRPNTFF

Ligand information

>7cpv Chain L7 (length=120) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gucuacggccauaccacccugaacgcgcccgaucucgucugaucucggaa
gcuaagcagggucgggccugguuaguacuuggaugggagaccgccuggga
auaccgggugcuguaggcuu

<<<<<<<<<....<<<<<<<<.....<<<<<..............>>>..
>>....>>>>>>.>><<<<<<<.....<<.<<..<<....>>.>>.>>..
..>>>>>>>>>>>>>>>>..

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7cpv A male germ-cell-specific ribosome controls male fertility.
Resolution	3.03 Å
Binding residue (original residue number in PDB)	S42 R43 Y46 S49 K53 K55 K56 S57 R87 R120 H122
Binding residue (residue number reindexed from 1)	S41 R42 Y45 S48 K52 K54 K55 S56 R86 R119 H121

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0014069	postsynaptic density
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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External links

PDB	RCSB:7cpv, PDBe:7cpv, PDBj:7cpv
PDBsum	7cpv
PubMed	36517592
UniProt	P62717\|RL18A_MOUSE Large ribosomal subunit protein eL20 (Gene Name=Rpl18a)

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