Structure of PDB 6y2l Chain LR Binding Site BS02

Receptor Information
>6y2l Chain LR (length=176) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLII
RKPVTVHSRARCRKNTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMRI
LRRLLRRYRESKKIDRHMYHSLYLKVKGNVFKNKRILMEHIHKLKADKAR
KKLLADQAEARRSKTKEARKRREERL
Ligand information
>6y2l Chain S2 (length=1713) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgcacuuggauaacugugguaa
uucuagagcuaauacaugccgacgggcgcugacccccuucgcggggggga
ugcgugcauuuaucaguggugacucuagauaaccucgggccgaucgcacg
ccccccguggcggcgacgacccauucgaacgucugcccuaucaacuuucg
augguagucgccgugccuaccauggugaccacgggugacggggaaucagg
guucgauuccggagagggagccugagaaacggcuaccacauccaaggaag
gcagcaggcgcgcaaauuacccacucccgacccggggagguagugacgaa
aaauaacaauacaggacucuuucgaggcccuguaauuggaaugaguccac
uuuaaauccuuccgcgaggauccauuggagggcaagucuggugccagcag
ccgcgguaauuccagcuccaauagcguauauuaaaguugcugcaguuaaa
aagcucguaguuggaucuugggagcgggcguccccgccccucucggcgcc
cgaagcauuuacuuugaaaaaauuagaguguucaaagcaggcccgagccg
ccuggauaccgcagcuaggaauaauggaauaggaccgcgguucuauuuug
uugguuuucggaacugaggccaugauuaagagggacggccgggggcauuc
guauugcgccgcuagaggugaaauucuuggaccggcgcaagacggaccag
agcgaaagcauuugccaagaauguuuucauuaaucaagaacgaaagucgg
agguucgaagacgaucagauaccgucguaguuccgaccauaaacgaugcc
gacuggcgaugcggcggcguuauucccaugacccgcgggcagcuuccggg
aaaccaaagucuuuggguuccggggggaguaugguugcaaagcugaaacu
uaaaggaauugacggaagggcaccaccaggaguggagccugcggcuuaau
uugacucaacacgggaaaccucacccggcccggacacggacaggauugac
agauugauagcucuuucucgauuccgugggugguggugcauggccguucu
uaguugguggagcgauuugucugguuaauuccgauaacgaacgagacucu
ggcaugcuaacuaguuacgcgacccccgagcggucggcguccaacuucuu
agagggacaaguggcguucagccacccgagauugagcaauaacaggucug
ugaugcccuuagauguccggggcugcacgcgcgcuacacugacuggcuca
gcgugugccuacccuacgccggcaggcgcggguaacccguugaaccccau
ucgugauggggaucggggauugcaauuauuccccaugaacgaggaauucc
caguaagugcgggucauaagcuugcguugauuaagucccugcccuuugua
cacaccgcccgucgcuacuaccgauuggaugguuuagugaggcccucgga
ucggccccgccggggcccuggcggagcgcugagaagacggucgaacuuga
cuaucuagaggaaguaaaagucguaacaagguuuccguaggugaaccugc
ggaaggaucauua
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<.<....<<....<<<<<.........<<....<<<.<<....
...>>.>>.>....>>.........<<<<...<<<<........>>>>..
.>>>><<..<<<<<...<......>..>>>>>......>>...<<<<.<<
<<......>>>>>>>>.>>.>>>...>>..>.>>>.<<<....<<<....
<<<<<<<.........>>>>>>>>>>......>>>...<<<.<<<<....
>>>>....>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>
...>>>>>>.........<<<....<<<.....>>>..>>>..>...>>.
>.....<<.<<<<<<............>>.>>>>..>>......<<..<.
..........>..>>.........<<<<<((......<<<<.....<<..
))>>.......>>>>.>>>>>..>>>>>>.>>>.........<.<((...
..<.<<...<<<.<<........<..........>...............
........<<<<<<.<.......<<...<.......>.<<<<.......>
>>>...>>......>.>>>..>>>........<.<<.<<<<<<.......
..........>>>>>>.>>.>....>>....<<<<<<..<...<<<<..<
<..<<<<<<<<...<<<......>>>......>>>>>>>>..>>......
.<<....>>...>>>>..>..>>>.>>>...>>>...>>.>....<<<<<
<<...<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<
.<<.<<<..<.<.<<<<.<<<<......>>>>>>>>>.>..>>>...<<.
.))>>...>>.....>>>.>.>.<<<......<<<......>>>....>>
>..)))).]<<<<<.<<<<<<<..<<..<<<<<..<<<.<<<<.......
.<<........>>..........<<<<<......<<<<<<.......<<.
<<<........>>>.>>.....>>>>>>...<<.<<<..<<.<<<<<<..
..<<<.<<<<<....>>>...<<<......>>>...>>.>>>....<<<.
..<...<<<<..<<<<<<<<<<<<.......>>>>.>>>>..>>>>..>>
>>..>.....<<<<<.....>>>>>........>>>....>>>.>>>...
..>>>>>>>.......>>>>>......>>>>.>>>.....<<.<<<....
....<.......<<<.<<<<....>>>>.>>>....>.........>>>.
>>............<<<<<..........>>>>>...........>>>>>
.....<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.
>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<.<<...
<<<<<......................>>>>>...>>.>>>>..>>>.>>
>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<<..>>>>>>
>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6y2l Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		A159 R162 R163 K165 T166 R172 R173 R176
Binding residue
(residue number reindexed from 1)		A158 R161 R162 K164 T165 R171 R172 R175
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0045202 synapse
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6y2l, PDBe:6y2l, PDBj:6y2l
PDBsum6y2l
PubMed32268098
UniProtP84098|RL19_HUMAN Large ribosomal subunit protein eL19 (Gene Name=RPL19)

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