Structure of PDB 7mq8 Chain LP Binding Site BS02

Receptor Information
>7mq8 Chain LP (length=567) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAEIIQERIEDRLPELEQLERIGLFSHAEIKAIIKKASDLEYKIQRRTLF
KEDFINYVQYEINLLELIQRRRTRIGYSFKKDEIENSIVHRVQGVFQRAS
AKWKDDVQLWLSYVAFCKKWATKTRLSKVFSAMLAIHSNKPALWIMAAKW
EMEDRLSSESARQLFLRALRFHPECPKLYKEYFRMELMHAEKLRKEKEEF
SEEILKGELAWIIYKNSVSIIKGAEFHVSLLSIAQLFDFAKDLQKEIYDD
LQALHTDDPLTWDYVARRELEQAKAVEVGRKEERCCAVYEEAVKTLPTEA
MWKCYITFCLERFTKLRGKRLERTMTVFRKAHELKLLSECQYKQLSVSLL
CYNFLREALEVAVAGTELFRDSGTMWQLKLQVLIESKSPDIAMLFEEAFV
HLKPQVCLPLWISWAEWSEGAKSQEDTEAVFKKALLAVIGADSVTLKNKY
LDWAYRSGGYKKARAVFKSLQESRPFSVDFFRKMIQFEKEQESCNMANIR
EYYERALREFGSADSDLWMDYMKEELNHPLGRPENCGQIYWRAMKMLQGE
SAEAFVAKHAMHQTGHL
Ligand information
>7mq8 Chain L2 (length=215) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gacuauacuuucagggaucauuucuauaguguguuacuagagaaguuucu
cugaacguguagagcaccgaaaaccacgaggaagagagguagcguuuucu
ccugagcgugaagccggcuuucuggcguugcuuggcugcaacugccguca
gccauugaugaucguucuucucuccguauuggggagugagagggagagaa
cgcggucugaguggu
..................................................
.......................<<<<.....<<.......<<<<<<<<<
<<<....<.......<<<<....<<<<<<<<......>>>>>.>>>...>
>>>.........>..<<<<<<<<<<.....>>>>>>.>>>>>>>>>>>>>
>>>...>>..>>>>.
Receptor-Ligand Complex Structure
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PDB7mq8 Nucleolar maturation of the human small subunit processome.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		M1 R47
Binding residue
(residue number reindexed from 1)		M1 R47
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0030515 snoRNA binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0032040 small-subunit processome
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7mq8, PDBe:7mq8, PDBj:7mq8
PDBsum7mq8
PubMed34516797
UniProtQ9NYH9|UTP6_HUMAN U3 small nucleolar RNA-associated protein 6 homolog (Gene Name=UTP6)

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