Structure of PDB 8rxh Chain LJ Binding Site BS02

Receptor Information
>8rxh Chain LJ (length=135) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QANVKGCRFRVSVALPVGAVVNCADNTGAKNLYVISVKGYHGRLNRLPSA
ALGDMVMCSVKKGKPELRKKVLNAVIIRQRKSWRRKDGTVIYFEDNAGVI
VNPKGEMKGSGIAGPVAKESADLWPKISTHAPAIV
Ligand information
>8rxh Chain L4 (length=184) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gugggauugugaagggaucucgcagguaucgugagggaaguaugggguag
uacgagaggaacucccaugccgugccucuaguuucugggguuugucgaac
ggcaagugccccgaagccaucgcacggugguucucggcugaacgccucua
agccagaagccaaucccaagaccagaugcccacu
<<<<<<<.........>>>>>>>.<<<<<<....<<<<.<<<<<<<<...
............>>>>>>>><<<<<...<.<<....<<<<<<<<<.....
.>>>>..>>>>>...>>.>..>>>>>.<<<<....<<<<...........
>>>>....>>>>.>>>>.......>>>>>>....
Receptor-Ligand Complex Structure
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PDB8rxh Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
Resolution2.93 Å
Binding residue
(original residue number in PDB)		N7 G10 C11 R12 F13 R14 S16 R47 R50 K85 R88 V94
Binding residue
(residue number reindexed from 1)		N3 G6 C7 R8 F9 R10 S12 R43 R46 K81 R84 V90
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8rxh, PDBe:8rxh, PDBj:8rxh
PDBsum8rxh
PubMed38722744
UniProtE9AFK3

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