Structure of PDB 8pfr Chain LI Binding Site BS02

Receptor Information
>8pfr Chain LI (length=290) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSSAYSSRFQTPFRRRREGKTDYYQRKRLVTQHKAKYNTPKYRLVVRFTN
KDIICQIISSTITGDVVLAAAYSHELPRYGITHGLTNWAAAYATGLLIAR
RTLQKLGLDETYKGVEEVEGEYELTEAVEDGPRPFKVFLDIGLQRTTTGA
RVFGALKGASDGGLYVPHSENRFPGWDFETEEIDPELLRSYIFGGHVSQY
MEELADDDEERFSELFKGYLADDIDADSLEDIYTSAHEAIRADPAFKPTE
KKFTKEQYAAESKKYRQTKLSKEERAARVAAKIAALAGQQ
Ligand information
>8pfr Chain LE (length=121) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguugcggccauaucuaccagaaagcaccguuucccguccgaucaacugu
aguuaagcugguaagagccugaccgaguaguguagugggugaccauacgc
gaaacucaggugcugcaaucu
<<<<<<<<<....<<<<<<<<.....<<.<<..............>>...
.>>....>>>>>>.>><<<<<<.......<<<<<..<<....>>.>>>>>
.....>>>>>>>>>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pfr Real-space refinement in PHENIX for cryo-EM and crystallography.
Resolution2.15 Å
Binding residue
(original residue number in PDB)		S13 S14 F16 T18 F20 R21 R22 R24 T28 Y30 R33 R54 T56 N57 K58 I61 Q63 I65 I69 D72 V74 Y79 H90 G91 N94 W95 Q151 R152 T154 T155 G156 A157 R158 Y198 H203 Y207 E210 E221 K224 T256 K258 F260 K262 Q264 Y265 A266 E268 S269 K270 Y272 R273 Q274 K276 L277 K279 R285 V286 K289
Binding residue
(residue number reindexed from 1)		S6 S7 F9 T11 F13 R14 R15 R17 T21 Y23 R26 R47 T49 N50 K51 I54 Q56 I58 I62 D65 V67 Y72 H83 G84 N87 W88 Q144 R145 T147 T148 G149 A150 R151 Y191 H196 Y200 E203 E214 K217 T249 K251 F253 K255 Q257 Y258 A259 E261 S262 K263 Y265 R266 Q267 K269 L270 K272 R278 V279 K282
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8pfr, PDBe:8pfr, PDBj:8pfr
PDBsum8pfr
PubMed
UniProtP26321|RL5_YEAST Large ribosomal subunit protein uL18 (Gene Name=RPL5)

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