Structure of PDB 7cpu Chain LG Binding Site BS02

Receptor Information
>7cpu Chain LG (length=229) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKV
PPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKRPPVLR
AGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGK
ARLGHLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHW
GGNVLGPKSVARIAKLEKAKAKELATKLG
Ligand information
>7cpu Chain L8 (length=156) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccggguuccucccggggcuacgccugucugagc
gucgcu
.........................................<<<<<<<<<
....>>>>.....<.<<<......>>.............>>>..>...>>
>....<<....>><<<<<<<<<.....>>>>>>>>>..............
......
Receptor-Ligand Complex Structure
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PDB7cpu A male germ-cell-specific ribosome controls male fertility.
Resolution2.82 Å
Binding residue
(original residue number in PDB)		T52 W57 Y60 I61 Q64 R65 H159 D160 K185 R189
Binding residue
(residue number reindexed from 1)		T26 W31 Y34 I35 Q38 R39 H122 D123 K148 R152
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0042254 ribosome biogenesis
GO:0140236 translation at presynapse
GO:0140242 translation at postsynapse
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0045202 synapse
GO:0098793 presynapse
GO:0098794 postsynapse
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cpu, PDBe:7cpu, PDBj:7cpu
PDBsum7cpu
PubMed36517592
UniProtP12970|RL7A_MOUSE Large ribosomal subunit protein eL8 (Gene Name=Rpl7a)

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