Structure of PDB 8pv4 Chain LD Binding Site BS02

Receptor Information
>8pv4 Chain LD (length=286) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLVKNSAYYSRFQTKFKRRRQGKTDYYARKRLITQAKNKYNAPKYRLVVR
FTNRDIITQMVTSEINGDKIFAAAYSHELRAYGINHGLTNWAAAYATGLL
LARRVLAKLGLDGEYTLTEAAETEDGERRPFKAILDVGLARTSTGARVFG
VMKGASDGGIFIPHSENRFPGYDIETEELDTEVLKKYIYGGHVAEYMETL
ADDDEERYKSQFVKYIEDDVEADSLEELYAEAHKQIRADPFRKYVSDAPK
KSKEEWKAESLKYKKAKLSREERKARVEAKIKQLLA
Ligand information
>8pv4 Chain C4 (length=119) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acguacgaccauacccaguggaaagcacggcaucccguccgcucugcccu
aguuaagccacugagggcccgguuaguaguugggucggugacgaccagcg
aaucccggguguuguacgu
<<<<<<<<<....<<<<<<<<.....<<<<<<............>>>>..
.>>....>>>>>>.>><<<<<<......<<<<.<<<<....>>>>>>>>.
....>>>>>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB8pv4 Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		K8 S10 Y13 S14 T18 F20 K21 R22 R24 T28 Y30 R33 R50 R54 T56 N57 R58 I61 Q63 G71 D72 K73 I74 G91 N94 W95 R155 T158 A160 R161 Y201 H206 Y210 R221 Q225 V227 K228 Y229 K264 K267 W270 K271 S274 Y277 K278 K281 L282 R284 R287 R290
Binding residue
(residue number reindexed from 1)		K4 S6 Y9 S10 T14 F16 K17 R18 R20 T24 Y26 R29 R46 R50 T52 N53 R54 I57 Q59 G67 D68 K69 I70 G87 N90 W91 R141 T144 A146 R147 Y187 H192 Y196 R207 Q211 V213 K214 Y215 K250 K253 W256 K257 S260 Y263 K264 K267 L268 R270 R273 R276
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:8pv4, PDBe:8pv4, PDBj:8pv4
PDBsum8pv4
PubMed37921038
UniProtG0SEG2

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