Structure of PDB 8rxx Chain LA Binding Site BS02 |
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| >8rxx Chain L2 (length=1149)
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cccaacugcagaccguacucaucaccgcaucagguccccaagcauagaau
gcucugguacauagagaaagguacacucagggaagucggcaaaauagaug
cguaaguucgcaagaagcauuggcucugagggcaaaaaauugccaacuca
gaacugcuuacggcggggaauccaacuguauaauuaaaacauagguuugu
gaugcauccaagugguguauaucgcaaacugauuucugcccagugcucug
gucaacgugacgagauucaccgacgcgcggguaaacggcgggaguaacua
ugacucucuuaagguagccaaaugccucgucuuccaauuagagacgcgca
ugaauggauuaaugagauucccucugucccgaguuacuaucuagcgaaac
gacagucaagggaacggacuugaagggcuaagcggggaaagaagacccug
uugaguuugacuccagucuggcucugugcggcgacaucugaggcucggaa
cguugcuucacuuaucgaaugaagagaccaauggguuuagcguagucuuc
gggcuaugcaccgucuagguuugggaguccccuguggguacccaaccgug
cuguaaacugaaccaacgggaucaguuccggagucuuguuucgagacacu
gccagauggggaguuuggcuggggcggcauaucuguuacacgacaacgca
gguguccuaaggcgagcucagugggaacagaaaucucacguagaacacaa
gcguaaaagcuugcuugauuaacgauuuccaguacgaaucgagacugcga
aagcaaggccagcgauccuuugcgaagaauaggaaauaugaacaaaucau
accagaggugucagaauaauuaccacagggauaacuggcuuguggcggcc
aagcguucauagcgacgucgcuuuuugauccuucgaugucggcucuuccu
aaccuagcgccgcagaagacgcuaaggguuggauuguucacccacugaca
gggaacgugagcuggguuuagaccgucgugagacagguugguuuuacccu
acuuagcuggaaauugcgagaaaaagauuauccgugcaaagcggacgucg
ggucguugggccuggcgagcgguggguaguacaugguacgcucaucacc |
........................<<......>>......<<<<.....>
>>>........<<<<....<<<<.<<<<.<<.........<.....<<<<
<...............>>>>><<.<<<<<<<<<<<....>>>>>..>>>>
>>.>>..........<<<<<<<<<..<<<.........>>>..<<<<<<<
....<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<..
<<....<<<<......>>>>....>>..>>>>..>>>>><<<<<<.....
..>>>>>>........<...........<<<<<.......>>>>>.....
>.....>>....>>.>>>>>>>..>..>>.>>>>>>>>.>>>>.......
.....<<<<<........>>>>>..<<<<<<<..<<<.<<......<<<<
.<<<<<<..<<<<<.<<<<<<<...<<<.<<<<<<.<<<.<<.>>.>>>.
.>>>>>>.>>>...<<<<<.....<<<<....<<.....<<<<<<<<...
.>>>>>>>>.>>.....<<<<.<<...<<.<..>.>>...>>.>>>>...
................<<<<<....>>>>>..>>>>...>>>>>......
>>>>>>>..>>>>>...<<<.....>>>..<<<<<<...........>>>
>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.....<<....
..>>....>>>>>>>...<<...<<<<<.......>>>>>..>>.<<<..
..>>>.>>........<<<<<<..............<<<<.......>>>
>.>>>>>>.........>>>>..>>>>>>.......<<.<...<<<<<<.
..<<.......>>...>>>>>>....>.>.>.......<<<<<.<<<<<<
..<<<<<<<.<......>.>>>>>..>>.<<<.........>>>.....>
>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....>>..>>>
.>>>>>>>.......................<<<<.....>>>>.<<<<<
<<<<....>>>>>>>>>.<.<<<<<<<.<<<<...>>>>>>>>>>>.>. |
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| PDB | 8rxx Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. |
| Resolution | 2.97 Å |
Binding residue
(original residue number in PDB) | G2 S7 C8 G11 N12 G13 Q17 V18 G20 R23 G25 I31 Y34 R37 G39 Y40 K46 R54 R64 Y67 F69 F83 T84 G85 Q86 S87 K93 P95 K119 R123 T125 L126 A127 R128 A129 S130 G131 D132 L150 P151 S152 Q154 K156 G172 G173 R174 I175 V179 L180 A182 S185 K192 R193 W196 P197 K198 V199 R200 G201 V202 P206 H209 H211 G213 G214 N215 H216 Q217 H218 I219 G220 H221 P222 S223 T224 V225 S226 R227 H228 P230 P231 G232 Q233 K234 V235 G236 L237 I238 A239 A240 R241 R242 T243 G244 R245 I246 K253 G254 |
Binding residue
(residue number reindexed from 1) | G1 S6 C7 G10 N11 G12 Q16 V17 G19 R22 G24 I30 Y33 R36 G38 Y39 K45 R53 R63 Y66 F68 F82 T83 G84 Q85 S86 K92 P94 K118 R122 T124 L125 A126 R127 A128 S129 G130 D131 L149 P150 S151 Q153 K155 G171 G172 R173 I174 V178 L179 A181 S184 K191 R192 W195 P196 K197 V198 R199 G200 V201 P205 H208 H210 G212 G213 N214 H215 Q216 H217 I218 G219 H220 P221 S222 T223 V224 S225 R226 H227 P229 P230 G231 Q232 K233 V234 G235 L236 I237 A238 A239 R240 R241 T242 G243 R244 I245 K252 G253 |
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| Enzyme Commision number |
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