Structure of PDB 8rxh Chain LA Binding Site BS02 |
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| >8rxh Chain L2 (length=1155)
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cccaacugcagaccguacucaucaccgcaucagguccccaagcauagaau
gcucugguacauagagaaagguacacucagggaagucggcaaaauagaug
cguaaguucgcaagaagcauuggcucugagggcaaaaaauugccaacuca
gaacugcuuacggcggggaauccaacuguauaauuaaaacauagguuugu
gaugcauccaagugguguauaucgcaaacugauuucugcccagugcucug
aaugucaacgugacgagauucaccgacgcgcggguaaacggcgggaguaa
cuaugacucucuuaagguagccaaaugccucgucuuccaauuagagacgc
gcaugaauggauuaaugagauucccucugucccgaguuacuaucuagcga
aacgacagucaagggaacggacuugaagggcuaagcggggaaagaagacc
cuguugaguuugacuccagucuggcucugugcggcgacaucugaggcucg
gaacguugcuucacuuaucgaaugaagagaccaauggguuuagcguaguc
uucgggcuaugcaccgucuagguuugggaguccccuguggguacccaacc
gugcuguaaacugaaccaacgggauugcaguuccggagucuuguuucgag
acaucugccagauggggaguuuggcuggggcggcauaucuguuacacgac
aacgcagguguccuaaggcgagcucagugggaacagaaaucucacguaga
acacaagcguaaaagcuugcuugauuaacgauuuccaguacgaaucgaga
cugcgaaagcaaggccagcgauccuuugcgaagaauaggaaauaugaaca
aaucauaccagaggugucagaauaauuaccacagggauaacuggcuugug
gcggccaagcguucauagcgacgucgcuuuuugauccuucgaugucggcu
cuuccuaaccuagcgccgcagaagacgcuaaggguuggauuguucaccca
cugacagggaacgugagcuggguuuagaccgucgugagacagguugguuu
uacccuacuuagcuggaaauugcgagaaaaagauuauccgugcaaagcgg
acgucgggucguugggccuggcgagcgguggguaguacaugguacgcuca
ucacc |
........................<<......>>......<<<<.....>
>>>........<<<<....<<<<.<<<<.<<.........<.....<<<<
<.....<..>......>>>>><<.<<<<<<<<<<<....>>>>>..>>>>
>>.>>..........<<<<<<<<<..<<<.........>>>..<<<<<<<
....<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<..
..<<<....<<<<......>>>>....>>>.>>>>..>>>>><<<<<<..
.....>>>>>>........<...........<<<<<.......>>>>>..
...>.....>>....>>.>>>>>>>..>..>>.>>>>>>>>.>>>>....
........<<<<<........>>>>>..<<<<<<<..<<<.<<......<
<<<.<<<<<<..<<<<<.<<<<<<<...<<<.<<<<<<.<<<.<<.>>.>
>>..>>>>>>.>>>...<<<<<.....<<<<....<<.....<<<<<<<<
....>>>>>>>>.>>.....<<<<.<<...<<.<..>.>>...>>.>>>>
...................<<<<<......>>>>>..>>>>...>>>>>.
......>>>>>>>..>>>>>...<<<.....>>>..<<<<<<........
...>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.....
<<......>>....>>>>>>>...<<...<<<<<.......>>>>>..>>
.<<<....>>>.>>.........<<<<<..............<<<<....
...>>>>.>>>>>..........>>>>..>>>>>>.......<<.<.<.<
<<<<<...<<.......>>...>>>>>>...>>.>.>.......<<<<<.
<<<<<<..<<<<<<<.<......>.>>>>..>>>.<<<.........>>>
.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....>
>..>>>.>>>>>>>.......................<<<<.....>>>>
.<<<<<<<<<....>>>>>>>>>.<.<<<<<<<.<<<<...>>>>>>>>>
>>.>. |
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| PDB | 8rxh Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. |
| Resolution | 2.93 Å |
Binding residue
(original residue number in PDB) | G2 S7 C8 G11 N12 G13 Q17 V18 G20 R23 G25 P26 I31 Y34 R37 G39 Y40 R54 R64 Y67 K68 F69 F83 T84 G85 Q86 S87 K93 P95 K119 D122 R123 T125 L126 A127 R128 A129 S130 D132 L150 P151 S152 Q154 K156 R174 I175 V179 L180 A182 S185 K192 R193 W196 P197 K198 V199 R200 G201 V202 H211 G213 G214 N215 H216 Q217 H218 I219 G220 H221 P222 S223 T224 V225 S226 R227 H228 P230 P231 G232 Q233 K234 V235 G236 L237 I238 A239 A240 R241 R242 T243 G244 R245 I246 K253 G254 A255 H257 |
Binding residue
(residue number reindexed from 1) | G1 S6 C7 G10 N11 G12 Q16 V17 G19 R22 G24 P25 I30 Y33 R36 G38 Y39 R53 R63 Y66 K67 F68 F82 T83 G84 Q85 S86 K92 P94 K118 D121 R122 T124 L125 A126 R127 A128 S129 D131 L149 P150 S151 Q153 K155 R173 I174 V178 L179 A181 S184 K191 R192 W195 P196 K197 V198 R199 G200 V201 H210 G212 G213 N214 H215 Q216 H217 I218 G219 H220 P221 S222 T223 V224 S225 R226 H227 P229 P230 G231 Q232 K233 V234 G235 L236 I237 A238 A239 R240 R241 T242 G243 R244 I245 K252 G253 A254 H256 |
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| Enzyme Commision number |
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