Structure of PDB 8fku Chain L9 Binding Site BS02 |
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| >8fku Chain L3 (length=2185)
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gcgaccucagaucagacguggcgacccgcugaaagcauauuagucagcgg
aggagaagaaacuaaccaggauucccucaguaacggcgagugaacaggga
agagcccagcgccgaauccccgccccgggggcgcgggacauguggcguac
ggaagacccgcuccccggcgccgcucguggggggcccaaguccuucugau
cgaggcccagcccguggacggugugaggccgguagcggcccccggcgcgc
cgggcccgggucuucccggagucggguugcuugggaaugcagcccaaagc
gggugguccaucuaaggcuaaauaccggcacgagaccgauagucaacaag
uaccguaagggaaaguugaaaagaacuuugaagagagaguucaagagggc
gugaaaccguuaagaggaacgggugggguccgcgcaguccgcccggagga
uucaacccggcggcggccgccgccgggcgcauuuccaccgcggcggugcg
ccgcgaccggcuccgggacggcugggaaggcccggcggggaagguggcuc
gggcccgaguguuacagcccccccggcagcagcacucgccgaaucccggg
gccgagggagcgccgcgcucuccggccgggccaggccacggagcgcacgg
ggucggcggcgacgucggcuacccacccgacccgucuugaaacacggacc
aaggagucuaacacgugcgcgagucgggggcucgcacgaaagccgccgug
gcgcaaggugggaucccgaggcccgccgagggcgcaccaccggcccgucu
cgcccggggagguggagcacgagcgcacguguuaggacccgaaagauggu
gaaaccaucuaguagcugguucccuccgaaguuucccggauagcuggcgc
ucuccgcaguuuuauccgguggguaagaagcccggcucgagccgggcgug
gaaugcgagugccuagugggccacuuuugguaagcagaacuggcgcugcg
ggaugaaccgaacgccggguuaaggcgcccgaugccgacgcucaucagac
cccagaaaagguguugguugauauagacagcaggacgguggccauggaag
ucggaauccgcuaaggaguguguaacaacucaccugccgaaucaacuagc
ccugaaaauggauggcgcuggagcgucgggcccauacccggccgucgccg
gcagucacgcuacgccgcgacgaguaggagggccgcugcggugagccuug
aagccuagggcgcgggcccggguggagccgccgcaggugcagaucuuggu
gguaguagcaggggcgauggccuccggcccucgcggagaugggcgccgcg
aggcguccagugaaucucgcauguagguaagggaaguacugucccuaccu
acuauccagcgaaaccacagccaagggaacgggcuuggcggaaucagcgg
ggagaagacccuguugagcuugacucuagucuggcacggugaagagacau
gagagguguagaauaagugggaggcggccgccggugaaauaccacuacuc
ugaucguuuuuuccagugccagguggggaguuauccuucugaccuuuugg
guuuuaagcaggaggugucagaaaaguuaccacagggauaacuggcuugu
ggcggccaagcgcgacgucgcuuuuugaugaugucggcucuuccuaucau
ugugaagcagaauucaccaagcguuggauuguucacccacuaauagggaa
cgugagcuggggucgugagaccccuacugaugguuguugccaugguaauc
cugcucaguacgagaggaaccgcagguucagacauuugguggugcuuggc
ugaggagccaauggggcgaagcuaccaucugugggauuaugacugaacgc
cucuaagucagaaucccgcccaggcggaacgauaagcgccgcggagccuc
gguuggccucggauagccgguccccgggguccggugcggagugcccuucg
uccugggaaacggggcgcggccggagaggcggccgcccccucgcccguca
cgcaccgcacguucguggggaaccuggcgcuaaaccauucguagacgacc
ugcuucugggucgggguuucguacguagcagagcagcucccucgcugcga
ucuauugaaagucagcccucgacacaaggguuugu |
........................<<<<<<...............>>>>>
.>.........<<....>>..<<<<<<.....<<.....>>....>>>>>
>..<<<..<<<<<...<<<<<<<<<<.>>>>>>.>>>>.....>>>>>..
<<<<<<<<<<...<<<<<<<<.<<.....<<<<<<<<....<<<<.....
.>>>>.....((......<<<.....))>>>...>.>>>>>>>.>>>>>>
>>>>..>>>>>>>>>>.......<<<<<<<........>>>>>>>.....
<<<<<<.>>>>>>..>>>................................
..<<....>>...............<<<<....>>>>.............
...................<<<<<<<<..<<<.<<...<<<<<<<<.<<<
.....<<<<<<<<<<..>>>>>>>>>>......>>>.>>>.>>>>>...<
<<<<<<.<<<<<<<<<<<<<<<...<<..<<<.<<.<<<<......<<<<
<<..>>>>>>.......>>>>>>.>>>........>>>>>>..>>>>>>>
>>>>..........<<<<<<.<..>.<<<<<<.>>>>.>>>>>>>>....
..>>.>>>>>...>>>>>...>>>>>>>>..<<<<.<....>.>>>><<<
<<<....<<<<<<<<<<<<<..<<<...<<<<........>>>>.....>
>>....<<<<<...<<<..<<<..>>>..>>>....>>>>>.<<<<<<<<
<.<<..>>>>>>>>>.>>....>>>>>>>>>>>>>..<<.<...<<<<<<
...>>>>>>......>.>>..<<<<<<....<.<<<.>>>.><<.<<<<<
<<...<<<.<<<<<<<<...>>>>>>...<<<<<<<<..>>>>>>>>...
.>>>>>>>>>>>>..>>..<<<<.<<<<<.....>>>>>.>>>>....<<
<......>>>...<<<<<<<...<<<(((.......<<<<<.....<<..
........<<<.<<<<<<<<<<.....<.<<<<<.<<....<<.......
..>>....>>.........<<......>>...>>>>>.>.>>>>>>>>>>
>>>..........))).>>...>>>>>..>>>...>>>>>>><<<<<<.<
<<...........>>>>>>>>>....>>>>>>.<.<<<<<<<<.<<....
..<<<<.<<<<....>>>>>>>>...>>>>>>>>>>..>.....>>>>>>
<<<....<...<<<<...........>>>>..<<<<<...<<<<<<<...
.>>>>>>>......>>.>>>..<<<<<<.<<<<<<<..>>.>>>>>>>>>
>>.......>...>>>...<<<<<<........>>>>>>....<<<<.<<
<<......<<<<<<.<<<<<<.<<<<<.<<<<<<<<<...<<<<<<<<<<
.<<<<..........<<<<<..<<<.>>>............>>>>>.>>>
>.>>.>>>>>>>>..>>>>>>>>>..>>>>>...<<<<<<<..<<<....
.....>>>>>>>>>>........>>>>>.>.>>>>>>.............
<<<<<<...<..>...>>>>>>.......((...<<<<<<<<<<<..<.<
.<<<<<......>>>>>...>.>.<<<.....))..>>>.....>>>>>.
...>>>>>>..<<<....>>>>>>>.>>>>..<<<<<<.<..<<<..<.<
<<<<.................>>>>>.><<<<....<<<<.<<.<<<<<<
<....>>>>>..>>.>>...>>>>...>>>><<<<<...<<<<<......
.....>>>>>...>>>>>.>>>...>.>>>>>>.<<<<<<<.<<..<<<<
....<<<........<<<<<.<<<<>>>>.>>>>>.......>>>...<<
<..<<<<....<<<<.<<<<<<<......>>>>>>>>>>>...>>>>..>
>>..............>>>>..>>>>>>>>><<<<<.<............
.>....<<.<<<<<<<.<<.....<<<<....<<<<<......>>>>>..
.>>>>....>>....>>>>.>>>.>>..>>>>>.. |
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| PDB | 8fku Principles of human pre-60 S biogenesis. |
| Resolution | 2.82 Å |
Binding residue
(original residue number in PDB) | G2 Y4 Q8 R12 K14 Q15 P40 R41 R44 K47 R49 R50 L51 K54 A55 K56 R68 G69 K93 F94 A95 S97 R108 A112 W120 F138 R144 W150 H156 K157 H158 M161 R162 L164 R169 S171 R172 K176 G177 H178 K179 H181 H182 I184 G186 S187 R189 W192 R193 R195 H201 R202 Y203 R204 |
Binding residue
(residue number reindexed from 1) | G1 Y3 Q7 R11 K13 Q14 P39 R40 R43 K46 R48 R49 L50 K53 A54 K55 R67 G68 K72 F73 A74 S76 R87 A91 W99 F117 R123 W129 H135 K136 H137 M140 R141 L143 R148 S150 R151 K155 G156 H157 K158 H160 H161 I163 G165 S166 R168 W171 R172 R174 H180 R181 Y182 R183 |
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| Enzyme Commision number |
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