Structure of PDB 3ja1 Chain L2 Binding Site BS02

Receptor Information

>3ja1 Chain L2 (length=70) Species: 562 (Escherichia coli)

MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFFTGKQRD
VATGGRVDRFNKRFNIPGSK

Ligand information

>3ja1 Chain LB (length=120)

ugccuggcggccguagcgcgguggucccaccugaccccaugccgaacuca
gaagugaaacgccguagcgccgaugguaguguggggucuccccaugcgag
aguagggaacugccaggcau

<<<<<<<<<<.....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>>.<<.....<.<<<<<<<<...>>>>>>>>...
>...>>...>>>>>>>>>>.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3ja1 Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.
• Resolution: 3.6 Å
• Binding residue (original residue number in PDB): M1 K2 K3 I5
• Binding residue (residue number reindexed from 1): M1 K2 K3 I5

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0008270 zinc ion binding
• GO:0019843 rRNA binding
• GO:0046872 metal ion binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation
• GO:0006413 translational initiation
• GO:1904689 negative regulation of cytoplasmic translational initiation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:3ja1, PDBe:3ja1, PDBj:3ja1
• PDBsum: 3ja1
• PubMed: 26229983
• UniProt: P0A7M9|RL31_ECOLI Large ribosomal subunit protein bL31 (Gene Name=rpmE)