Structure of PDB 8hkz Chain L18P Binding Site BS02

Receptor Information
>8hkz Chain L18P (length=193) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TQGPNYRIKFRRRREGKTDYYTRYTYVINNAIRFVPRLTNKYVIVSVSKF
DQKGDIMIAYAHSIELVKKYGWKGDTNNTPAAYLTGYLAGLRAVKSGVKA
AVSDIGLFVPVKGGRIFAVIKGAIDAGLKVPVGDLGKLKDRVNGSHISAY
AQKLKNENQELYNKLFSSYIQRGLDPVLLPQHFEEVLNKIKEN
Ligand information
>8hkz Chain A5S (length=122) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugcccacccggucauagugagcggguaacacccggacucguuucgaaccc
ggaaguuaagccgcucacgucagaggggccgugggauccgagagggcccg
cagccucucugagcugggaugg
......<<.<......<<<<<<<<.....<<<<<...............>
>>..>>....>>>>>>>>.<<<<<.<<<<.<<<<<..<<....>>.>>>>
>.>>>>.>>>>>..>.>>....
Receptor-Ligand Complex Structure
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PDB8hkz Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome.
Resolution4.78 Å
Binding residue
(original residue number in PDB)		T2 G4 P5 Y7 I9 F11 R12 R13 R15 K18 T19 Y21 R24 R34 R38 N41 Y43 Q53 K54 G55 D56 I57 M58 Y61 H63 I65 D76 N79 T80 G115 R116 R142 H147 Y151 Y163 N164 K165 L166 F167
Binding residue
(residue number reindexed from 1)		T1 G3 P4 Y6 I8 F10 R11 R12 R14 K17 T18 Y20 R23 R33 R37 N40 Y42 Q52 K53 G54 D55 I56 M57 Y60 H62 I64 D75 N78 T79 G114 R115 R141 H146 Y150 Y162 N163 K164 L165 F166
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8hkz, PDBe:8hkz, PDBj:8hkz
PDBsum8hkz
PubMed37604686
UniProtO05640|RL18_SULAC Large ribosomal subunit protein uL18 (Gene Name=rpl18)

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