Structure of PDB 8ro2 Chain L Binding Site BS02

Receptor Information
>8ro2 Chain L (length=555) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLD
PSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLD
KAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEA
RARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRK
RGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGEASQDR
ILQEAQNLMALTNVDTPLKGGDVDARKQAIRDAERVKEMKRMHKAVQKDL
PRPSEVNETILRPLNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPS
GNKKGKTVGFGTNNSEHITYLEHNPYEKFSKEELKKAQDVLVQEMEVVKQ
GMSHGELSSEAYNQVWEECYSQVLYLPGQSRYTRANLAKKDRIESLEKRL
EINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAH
LELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYADLLLEKE
TLKSK
Ligand information
>8ro2 Chain 6 (length=97) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gugcucgcuucggcagcacauauacuaaaauuggaacgauacagagaaga
uuagcauggccccugcgcaaggaugacacgcaaauucgugaagcguu
<<<<<.<<....>>>>>>>...............................
......<<...<<<.....>>>....>>...................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ro2 Mechanism for the initiation of spliceosome disassembly.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		Q30 R33 R158 G164 K165 K166 R169 K170 R206
Binding residue
(residue number reindexed from 1)		Q25 R28 R153 G159 K160 K161 R164 K165 R201
External links
PDB RCSB:8ro2, PDBe:8ro2, PDBj:8ro2
PDBsum8ro2
PubMed38925148
UniProtQ99459|CDC5L_HUMAN Cell division cycle 5-like protein (Gene Name=CDC5L)

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