Structure of PDB 8ovj Chain L Binding Site BS02

Receptor Information
>8ovj Chain L (length=144) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PTRFKKCRHQRGSTFCGYGRVGKHRKHESGRGNAGGMHHHRINFDKYHPG
YFGKLGMDHYHRKKNPMWKPTINLNNLSRLIAAEEAAKAAKGGTLPVVDL
QSSGYAKLLGNGHIQVPCIVKARYVSKLADKKIRKAGGAVVLQA
Ligand information
>8ovj Chain 2 (length=1105) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccaacugcagaccguacucaucaccgcaucagguccccaagcauagaaug
cucugguacauagagaaagguacacucagggaagucggcaaaauagaugc
guaaguucgcaagaagcauuggcucugagggcaaaaauugccaacucaga
acugcuuacggcggggaauccaacuguauaauuaaaacauagguuuguga
ugcauccaagugguguauaucgcaaacugauuucugcccagugcucugaa
ugucaacgugacgagauucaccgacgcgcggguaaacggcgggaguaacu
augacucucuuaagguagccaaaugccucgucuuccaauuagagacgcgc
augaauggauuaaugagauucccucugucccgaguuacuaucuagcgaaa
cgacagucaagggaacggacuugaagggcuaagcggggaaagaagacccu
guugaguuugacuccagucuggcucugugcggcgacauccguugcuucac
uuaucgaaugaagagaccaauggguugcguagucuucgggcuaugcaccg
ucuagguuguggguacccaaccgugcuguaaacugaaccaacgggaguuc
cggagucuuguuucgagacaucugccagauggggaguuuggcuggggcgg
cauaucuguuacacgacaacgcagguguccuaaggcgagcucagugggaa
cagaucucacguagaacacaagcguaaaagcuugcuugauuaacgauuuc
caguacgaaucgagacugcgaaagcaaggccagcgauccuuugcgaagaa
uaggaaauaugaacaaaucauaccagaggugucagaauaauuaccacagg
gauaacuggcuuguggcggccaagcguucauagcgacgucgcuuuuugau
ccuucgaugucggcucuuccuaaccuagcgccgcagaagacgcuaagggu
uggauuguucacccacugacagggaacgugagcuggguuuagaccgucgu
gagacagguugguuuuacccuacuuagcuggaaauugcgagaaaaagauu
auccgugcaaagcggacguggcgagcgguggguaguacaugguacgcuca
ucacc
.......................<<......>>......<<<<<...>>>
>>........<<<<....<<<<.<<<<.<<.........<.....<<<<<
....<<..>>.....>>>>><<.<<<<<<<<<<<...>>>>>..>>>>>>
.>>..........<<<<<<<<<..<<<.........>>>..<<<<<<<..
..<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<....
<<<....<<<<......>>>>....>>>.>>>>..>>>>><<<<<<....
...>>>>>>........<...........<<<<<.......>>>>>....
.>.....>>....>>.>>>>>>>..>..>>.>>>>>>>>.>>>>......
......<<<<<........>>>>>..<<<<<<<..<<<.<<......<<<
<.<<<<<<..<<<<<.<<<<<<<...<<<.<<<<<<....>>>>>>.>>>
...<<<<<.....<<<<....<<...<<<<<<<<<..>>>>>>>>>.>>.
....<<<............>>>...................<<<<...>>
>>..>>>>...>>>>>.......>>>>>>>..>>>>>...<<<.....>>
>..<<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.
....>>>>>>.....<<......>>....>>>>>>>...<<...<<<<<.
......>>>>>..>>.<<<....>>>.>>.........<<<<<.......
.......<<<<.......>>>>.>>>>>..........>>>>..>>>>>>
.......<<.<.<.<<<<<<...<<.......>>...>>>>>>...>>.>
.>.......<<<<<.<<<<<<..<<<<<<<.<......>.>>>>..>>>.
<<<.........>>>.....>>>>>..>...>>>.>>....<<<<<<<..
..>>>.>>>>....>>..>>>.>>>>>>>.....................
..<<<<.....>>>>.<<<.>>>.<.<<<<<<<.<<<<...>>>>>>>>>
>>.>.
Receptor-Ligand Complex Structure
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PDB8ovj Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		R42 I43 G54 K55 G57 M58 H60
Binding residue
(residue number reindexed from 1)		R41 I42 G53 K54 G56 M57 H59
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:0043232 intracellular non-membrane-bounded organelle
GO:1990904 ribonucleoprotein complex

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ovj, PDBe:8ovj, PDBj:8ovj
PDBsum8ovj
PubMed38722744
UniProtE9AFK0

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