Structure of PDB 8b6c Chain L Binding Site BS02

Receptor Information

>8b6c Chain L (length=210) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

APSRNGMILKPHFHKDWQRRVATWFNQPARKIRRRKARQARARRIAPRPA
AGPIRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKVARTIGISVDPR
RRNKSTESLQANVQRLKEYRSKLVLFPRKPSAPKKGDSSAEELKLATQLT
GPVMPIRNVFKKEKARVITEEEKNFKAFASLRMARANARLFGIRAKRAKE
AAEQDVEKKK

Ligand information

>8b6c Chain 8 (length=151) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcagguugaucaucgacacuucgaac
gcacuugcggccccggguuccucccggggcuacgccugucugagcgucgc
u

.........................................<<<<<<<<<
....>>>>.....<.<<<......>>........>>>..>...>>>....
<<<..>>><<<<<<<<.......>>>>>>>>...................
.

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8b6c Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative.
Resolution	2.79 Å
Binding residue (original residue number in PDB)	A30 R34
Binding residue (residue number reindexed from 1)	A29 R33

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Cellular Component

External links

PDB	RCSB:8b6c, PDBe:8b6c, PDBj:8b6c
PDBsum	8b6c
PubMed	36867692
UniProt	G1TKB3\|RL13_RABIT Large ribosomal subunit protein eL13 (Gene Name=RPL13)

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