Structure of PDB 7r6t Chain L Binding Site BS02

Receptor Information

>7r6t Chain L (length=288) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRK
HCKFKPDPNIPPTFSAFNEDYVGSGWSRGAMAPAGNNKFSSKAMAETFYL
SNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKK
IVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQP
QLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLY
LSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYE

Ligand information

>7r6t Chain K (length=7) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

acgtcag

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7r6t Human EXOG possesses strong AP hydrolysis activity
Resolution	2.9 Å
Binding residue (original residue number in PDB)	K113 S172 L311 K315 R320
Binding residue (residue number reindexed from 1)	K53 S112 L251 K255 R260

Enzymatic activity

Enzyme Commision number

3.1.30.-

Gene Ontology

	Molecular Function
GO:0003676	nucleic acid binding
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

View graph for
Molecular Function

External links

PDB	RCSB:7r6t, PDBe:7r6t, PDBj:7r6t
PDBsum	7r6t
PubMed
UniProt	Q9Y2C4\|EXOG_HUMAN Nuclease EXOG, mitochondrial (Gene Name=EXOG)

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