Structure of PDB 7qwr Chain L Binding Site BS02

Receptor Information

>7qwr Chain L (length=210) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

APSRNGMILKPHFHKDWQRRVATWFNQPARKIRRRKARQARARRIAPRPA
SGPLRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKVARTIGISVDPR
RRNKSTESLQANVQRLKEYRSKLVLFPRKPSAPKKGDSSAEELKLATQLT
GPVMPIRNVFKKEKARVITEEEKNFKAFASLRMARANARLFGIRAKRAKE
AAEQDVEKKK

Ligand information

>7qwr Chain 8 (length=156) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccggguuccucccggggcuacgccugucugagc
gucgcu

.........................................<<<<<<.<<
.....>>>.....(.<<<......>>.............>>>..)...>>
>....<<<..>>><<<<<<<<.......>>>>>>>>..............
......

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7qwr Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting.
Resolution	2.9 Å
Binding residue (original residue number in PDB)	N27 A30 R34
Binding residue (residue number reindexed from 1)	N26 A29 R33

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Cellular Component

External links

PDB	RCSB:7qwr, PDBe:7qwr, PDBj:7qwr
PDBsum	7qwr
PubMed	35201867
UniProt	G1TKB3\|RL13_RABIT Large ribosomal subunit protein eL13 (Gene Name=RPL13)

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