Structure of PDB 6t90 Chain L Binding Site BS02

Receptor Information
>6t90 Chain L (length=74) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPF
IDEAKRLRALHMKEHPDYKYRPRR
Ligand information
>6t90 Chain J (length=141) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gatgtatatatctgacacgtgcctggagactagggagtaatccccttggc
ggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgctagagc
tgtctacgaccaattgagcggatttgcataacaaagtctcc
Receptor-Ligand Complex Structure
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PDB6t90 Mechanisms of OCT4-SOX2 motif readout on nucleosomes.
Resolution3.05 Å
Binding residue
(original residue number in PDB)
K42 R43 M45 M49 R53 K65 N68 Y110
Binding residue
(residue number reindexed from 1)
K2 R3 M5 M9 R13 K25 N28 Y70
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6t90, PDBe:6t90, PDBj:6t90
PDBsum6t90
PubMed32327602
UniProtP48431|SOX2_HUMAN Transcription factor SOX-2 (Gene Name=SOX2)

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