Structure of PDB 6psw Chain L Binding Site BS02

Receptor Information
>6psw Chain L (length=473) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EIGRTTDPVRMYMREMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPE
AITYLLEQYDRVEAEEARLSDLITGFVDDPELAREKFAELRAQYVVTRDT
IHATAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVMMDRVRTQERLIMKL
CVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKLHDVSEEVHRA
LQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISI
AKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAIT
RSIADQARTIRIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMP
EDKIRKVLKIAKEPISMETPIGDDEDSHLGDFIEDTTLELPLDSATTESL
RAATHDVLAGLTAREAKVLRMRFGIDMNTDYTLEEVGKQFDVTRERIRQI
EAKALRKLRHPSRSEVLRSFLDD
Ligand information
>6psw Chain P (length=62) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tatggacaattcaaaggccgaggaatatgcccttttagccttcttttgtc
aatggatttgtg
Receptor-Ligand Complex Structure
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PDB6psw Stepwise Promoter Melting by Bacterial RNA Polymerase.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		N396 R397 Q437 T509 G512 D513 E515 R562 T572 L573 R584 E585 R588
Binding residue
(residue number reindexed from 1)		N256 R257 Q297 T369 G372 D373 E375 R422 T432 L433 R444 E445 R448
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005515 protein binding
GO:0016987 sigma factor activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0009408 response to heat
GO:0010468 regulation of gene expression
GO:0045892 negative regulation of DNA-templated transcription
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0000345 cytosolic DNA-directed RNA polymerase complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:1903865 sigma factor antagonist complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6psw, PDBe:6psw, PDBj:6psw
PDBsum6psw
PubMed32160514
UniProtP00579|RPOD_ECOLI RNA polymerase sigma factor RpoD (Gene Name=rpoD)

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