Structure of PDB 6psu Chain L Binding Site BS02

Receptor Information
>6psu Chain L (length=529) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQLKLLVTRGKEQGYLTYAEVNDHLDQIEDIIQMINDMGIQVMEEDAAEA
AAQVLSSVTTDPVRMYMREMGTVELLTREGEIDIAKRIEDGINQVQCSVA
EYPEAITYLLEQYDRVEAEEARLSDLITGFVDIDPELAREKFAELRAQYV
VTRDTIKHATAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVMMDRVRTQE
RLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKLHDVS
EEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANL
RLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWW
IRQAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGREPTPEELA
ERMLMPEDKIRKVLKIAKEPISMETPIGDDEDSHLGDFIEDTTLELPLDS
ATTESLRAATHDVLAGLTAREAKVLRMRFGIDMNTDYTLEEVGKQFDVTR
ERIRQIEAKALRKLRHPSRSEVLRSFLDD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6psu Stepwise Promoter Melting by Bacterial RNA Polymerase.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		K393 Y394 R397 R436 T440 R465 R468 R562 T572 L573 R584 E585 R588
Binding residue
(residue number reindexed from 1)		K309 Y310 R313 R352 T356 R381 R384 R478 T488 L489 R500 E501 R504
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005515 protein binding
GO:0016987 sigma factor activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0009408 response to heat
GO:0010468 regulation of gene expression
GO:0045892 negative regulation of DNA-templated transcription
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0000345 cytosolic DNA-directed RNA polymerase complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:1903865 sigma factor antagonist complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6psu, PDBe:6psu, PDBj:6psu
PDBsum6psu
PubMed32160514
UniProtP00579|RPOD_ECOLI RNA polymerase sigma factor RpoD (Gene Name=rpoD)

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