Structure of PDB 6pst Chain L Binding Site BS02

Receptor Information
>6pst Chain L (length=558) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQLKLLVTRGKEQGYLTYAEVNDHLPEDIVDSDQIEDIIQMINDMGIQVM
EEAPDADDLMLAENTADEDAAEAAAQVLSSVESEIGRTTDPVRMYMREMG
TVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEA
RLSDLITGFVDIDPELAREKFAELRAQYVVTRDTIKHATAQEEILKLSEV
FKQFRLVPKQFDYLVNSMRVMMDRVRTQERLIMKLCVEQCKMPKKNFITL
FTGNETSDTWFNAAIAMNKPWSEKLHDVSEEVHRALQKLQQIEEETGLTI
EQVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAKKYTNRGLQFLDLI
QEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVH
MIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPI
SMETPIGDDEDSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTARE
AKVLRMRFGIDMNTDYTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSE
VLRSFLDD
Ligand information
>6pst Chain P (length=51) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caaaggccgaggaatgcgcccttttagccttcttttgtcaatggatttgt
g
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6pst Stepwise Promoter Melting by Bacterial RNA Polymerase.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		K393 Y394 N396 R397 W433 Q437 R468 R562 T572 L573 R584 E585
Binding residue
(residue number reindexed from 1)		K338 Y339 N341 R342 W378 Q382 R413 R507 T517 L518 R529 E530
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005515 protein binding
GO:0016987 sigma factor activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0009408 response to heat
GO:0010468 regulation of gene expression
GO:0045892 negative regulation of DNA-templated transcription
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0000345 cytosolic DNA-directed RNA polymerase complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:1903865 sigma factor antagonist complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6pst, PDBe:6pst, PDBj:6pst
PDBsum6pst
PubMed32160514
UniProtP00579|RPOD_ECOLI RNA polymerase sigma factor RpoD (Gene Name=rpoD)

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