Structure of PDB 3th3 Chain L Binding Site BS02

Receptor Information
>3th3 Chain L (length=96) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENG
GCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3th3 Chain L Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3th3 Mg2+ Is Required for Optimal Folding of the Gamma-Carboxyglutamic Acid (Gla) Domains of Vitamin K-Dependent Clotting Factors At Physiological Ca2+
Resolution2.7 Å
Binding residue
(original residue number in PDB)		G47 Q49 D63 Q64
Binding residue
(residue number reindexed from 1)		G1 Q3 D17 Q18
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.21.21: coagulation factor VIIa.
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:3th3, PDBe:3th3, PDBj:3th3
PDBsum3th3
PubMed
UniProtP08709|FA7_HUMAN Coagulation factor VII (Gene Name=F7)

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