Structure of PDB 3ogk Chain L Binding Site BS02

Receptor Information
>3ogk Chain L (length=566) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SCVATVDDVIEQVMTYITDPKDRDSASLVCRRWFKIDSETREHVTMALCY
TATPDRLSRRFPNLRSLKLKGKPRAAMFNLIPENWGGYVTPWVTEISNNL
RQLKSVHFRRMIVSDLDLDRLAKARADDLETLKLDKCSGFTTDGLLSIVT
HCRKIKTLLMEESSFSEKDGKWLHELAQHNTSLEVLNFYMTEFAKISPKD
LETIARNCRSLVSVKVGDFEILELVGFFKAAANLEEFCGGSLNEDIGMPE
KYMNLVFPRKLCRLGLSYMGPNEMPILFPFAAQIRKLDLLYALLETEDHC
TLIQKCPNLEVLETRNVIGDRGLEVLAQYCKQLKRLRIERGADEQGMEDE
EGLVSQRGLIALAQGCQELEYMAVYVSDITNESLESIGTYLKNLCDFRLV
LLDREERITDLPLDNGVRSLLIGCKKLRRFAFYLRQGGLTDLGLSYIGQY
SPNVRWMLLGYVGESDEGLMEFSRGCPNLQKLEMRGCCFSERAIAAAVTK
LPSLRYLWVQGYRASMTGQDLMQMARPYWNIELIPSRHPAHILAYYSLAG
QRTDCPTTVRVLKEPI
Ligand information
Ligand IDOGK
InChIInChI=1S/C18H27NO4/c1-3-10-7-13-12(5-6-15(13)20)14(8-10)16(21)19-18(17(22)23)9-11(18)4-2/h10-14H,3-9H2,1-2H3,(H,19,21)(H,22,23)/t10-,11+,12+,13+,14+,18+/m1/s1
InChIKeyYYTFHRRGIDEJIS-FNEQEMTHSA-N
SMILES
SoftwareSMILES
ACDLabs 12.01O=C(NC1(C(=O)O)CC1CC)C3CC(CC)CC2C(=O)CCC23
OpenEye OEToolkits 1.7.0CC[C@@H]1C[C@H]2[C@H](CCC2=O)[C@H](C1)C(=O)N[C@]3(C[C@@H]3CC)C(=O)O
CACTVS 3.370CC[CH]1C[CH]2[CH](CCC2=O)[CH](C1)C(=O)N[C]3(C[CH]3CC)C(O)=O
CACTVS 3.370CC[C@@H]1C[C@H]2[C@H](CCC2=O)[C@H](C1)C(=O)N[C@]3(C[C@@H]3CC)C(O)=O
OpenEye OEToolkits 1.7.0CCC1CC2C(CCC2=O)C(C1)C(=O)NC3(CC3CC)C(=O)O
FormulaC18 H27 N O4
Name(1S,2S)-2-ethyl-1-({[(3aS,4S,6R,7aS)-6-ethyl-1-oxooctahydro-1H-inden-4-yl]carbonyl}amino)cyclopropanecarboxylic acid;
Coronatine
ChEMBL
DrugBank
ZINCZINC000058638469
PDB chain3ogk Chain L Residue 1100 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3ogk Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		R85 F89 R348 A384 Y386 R409 Y444 L469 R496 W519
Binding residue
(residue number reindexed from 1)		R74 F78 R337 A373 Y375 R398 Y433 L458 R485 W508
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0006952 defense response
GO:0009611 response to wounding
GO:0009625 response to insect
GO:0009641 shade avoidance
GO:0009753 response to jasmonic acid
GO:0009861 jasmonic acid and ethylene-dependent systemic resistance
GO:0009867 jasmonic acid mediated signaling pathway
GO:0009901 anther dehiscence
GO:0009909 regulation of flower development
GO:0010118 stomatal movement
GO:0010218 response to far red light
GO:0016567 protein ubiquitination
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031348 negative regulation of defense response
GO:0042742 defense response to bacterium
GO:0048364 root development
GO:0048443 stamen development
GO:0050832 defense response to fungus
GO:0106167 extracellular ATP signaling
Cellular Component
GO:0019005 SCF ubiquitin ligase complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3ogk, PDBe:3ogk, PDBj:3ogk
PDBsum3ogk
PubMed20927106
UniProtO04197|COI1_ARATH Coronatine-insensitive protein 1 (Gene Name=COI1)

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