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Receptor Information

>8ip8 Chain KA (length=273) Species: 4565 (Triticum aestivum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QKTRAYSKRFQVKFKRRRQGKTDYRARLRLTNQDKNKYNTPKYRFVVRFT
NKDVTAQIVYATIAGDIVMAAAYSHELPRYGLEVGLTNYAAAYCTGLLLA
RRVLKCRDLDQEYEGNVEATGEDFSVEPADERRPFRALLDVGLIRTTTGN
RVFGALKGALDGGLDIPHSDKRFAGFKKDEKQLDAEIHRKYIYGGHVADY
MKSLADEEPEKYQSHFSEYIKKGIEADNMEALYKKVHAAIRADPTKRYNP
KKLTYEQRKASLVERLNALNSSA

>8ip8 Chain TB (length=120) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ggaugcgaucauaccagcacuaaggcaucggaucccgucagaacuccgaa
guuaagcgugcuugggcgagaguaguacaaggaugggugaccucuuggga
aguccucguguugcauuccc

<<<<<<<<<....<<<<<<<......<<<<<..............>>>..
>>.....>>>>>.>><<<<<.<.....<.<<<<.<<....>>>>>>.>..
..>.>>>>>>>>>>>>>>..

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8ip8 Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Resolution	2.9 Å
Binding residue (original residue number in PDB)	R10 S13 K14 F16 V18 F20 K21 R22 R24 T28 Y30 R33 R50 R54 T56 N57 K58 I69 A70 G71 D72 V74 Y79 N94 Y95 R151 T153 T154 N156 R157 Y197 H202 V203 Y206 H221 F222 S223 E224 Y225 K264 R265 Y266 N267 P268 K270 L271 Y273 R276 L280 R283
Binding residue (residue number reindexed from 1)	R4 S7 K8 F10 V12 F14 K15 R16 R18 T22 Y24 R27 R44 R48 T50 N51 K52 I63 A64 G65 D66 V68 Y73 N88 Y89 R145 T147 T148 N150 R151 Y191 H196 V197 Y200 H215 F216 S217 E218 Y219 K246 R247 Y248 N249 P250 K252 L253 Y255 R258 L262 R265

Enzyme Commision number

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0008097	5S rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:1990904	ribonucleoprotein complex

PDB	RCSB:8ip8, PDBe:8ip8, PDBj:8ip8
PDBsum	8ip8
PubMed	38267667
UniProt	W5BZZ2

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Structure of PDB 8ip8 Chain KA Binding Site BS02