Structure of PDB 8w1o Chain K Binding Site BS02

Receptor Information
>8w1o Chain K (length=1290) Species: 10905 (Bluetongue virus (serotype 1 / isolate South Africa)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VAITVQGAQLIKRVVERFYPGIAFNINEGACYIYKFSDHIRRIRMKHGTK
YRRQAEEIIRNISLRKERLYGIPVLDEVEWKYVFDGQTFQSYAFEVYVNS
ILPWSELDPEEEFLRNYRVSREMTEVEKFIEFRAKNEMQIYGDIPIKVWC
CFINELSAELKHVPLGMQVMADFVNRFDSPFHQGNRDLSNLEDFQVAYTT
PLLFEMCCMESILEFNIKMRMREEEISALEFGDMKVDPVGLLREFFILCL
PHPKKINNVLRAPYSWFVKMWGVGADPIVVLQSTAGDDRNSKDVFYDKFR
TEPNRYKALFRSSFYNESRRMNEEKILEAVKYSQKLGSHDRRLPLFEKML
KTVYTTPFYPHKSSNMILASFLLSIQTITGYGRAWVKNVSTEFDKQLKPN
PSNLVQDVSDLTREFFKQAYVEAKERREEIVKPEDLYTSMLRLTSSGFST
EIYVKKRFLIKINSRIKALVIFTKGHTVFTDEELHKKYNSVELYQTKGSR
DVPIKATRTIYSINLSVLVPQLIVTLPLNEYFSRVGGITSPDYKKIGGKV
IVGDLEATGSRVMDAADCFRNSADRDIFTIAIDYSEYDTHLTRHNFRTGM
LQGIREAMAPYRDLRYEGYTLEQIIDFGYGEGRVANTLWNGKRRLFKTTF
DAYIRLDESERDKGSFKVPKGVLPVSSVDVANRIAVDKGFDTLIAATDGS
DLALIDTHLSGENSTLIANSMHNMAIGTLMQREVGREQPGVLTFLSEQYV
GDDTLFYTKLHTTDTKVFDKVAASIFDTVAKCGHEASPSKTMMTPYSVEK
TQTHAKQGCYVPQDRMMIISSERRKDIEDVQGYVRSQVQTMITKVSRGFC
HDLAQLILMLKTTFIGAWKMKRTIKEDAMYRDRKFDSNDEDGFTLIQIRN
PLALYVPIGWNGYGAHPAALNIVMTEEMYVDSIMISKLDEIMAPIRRIVH
DIPPCWNETQGDKRGLISATKMSFFSKMARPAVQAALSDPQIINLVEELP
LGEFSPGRISRTMMHSALLKESSARTLLSSGYELEYQKALNSWITQVSMR
LGEESGVISTSYAKLFDVYFEGELDGAPHMFPDQNLSPQFYIQKMMIGPR
VSSRVRNSYVDRIDVILRKDVVMRGFITANTILNVIEKLGTNHSVGDLVT
VFTLMNIETRVAEELAEYMTSEKIRFDALKLLKKGIAGDEFTMSLNVATQ
DFIDTYLAYPYQLTKTEVDAISLYCTQMIMLRAALGLPKKKMKIVVTDDA
KKRYKIRLQRFRTHVPKIKVLKKLIDPNRMTVRNLENQFV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8w1o RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		T448 R512 I522 E568
Binding residue
(residue number reindexed from 1)		T444 R500 I510 E556
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0019079 viral genome replication

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8w1o, PDBe:8w1o, PDBj:8w1o
PDBsum8w1o
PubMed38614100
UniProtW0G557

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