Structure of PDB 8u5h Chain K Binding Site BS02

Receptor Information
>8u5h Chain K (length=110) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT
AEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLP
NIQSVLLPKC
Ligand information
>8u5h Chain C (length=157) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acgtaaacatcctggagaatcccggtgccgaggccgctcaattggtcgta
gacagctctagcaccgcttaaacgcacgtacgcgctgtcccccgcgtttt
aaccgccaaggggattactccctagtctccaggcacgtgtcagatatata
catcctg
Receptor-Ligand Complex Structure
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PDB8u5h Cryo-EM structure of human DNMT3A N-terminal domain bound to H2AK119Ub nucleosome
Resolution3.23 Å
Binding residue
(original residue number in PDB)
R11 R29 R42 V43 G44 A45 K75 T76
Binding residue
(residue number reindexed from 1)
R2 R20 R33 V34 G35 A36 K66 T67
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:8u5h, PDBe:8u5h, PDBj:8u5h
PDBsum8u5h
PubMed
UniProtP06897|H2A1_XENLA Histone H2A type 1

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