Structure of PDB 8imx Chain K Binding Site BS02

Receptor Information
>8imx Chain K (length=330) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GHTNNWAVLVCTSRFWFNYRHVANTLSVYRSVKRLGIPDSHIVLMLADDM
ACNPRNPKPATVFSHKNMELNVYGDDVEVDYRSYEVTVENFLRVLTGRIP
PSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDSEEITNIELADAFEQM
WQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPA
IGVHLMDRYTFYVLEFLEEINPASQTNMNDLFQVCPKSLCVSTPGHRTDL
FQRDPKNVLITDFFGSVRKVEITTETIKLQKLMEPLKYAEQLPVAQIIHQ
KPKLKDWHPPGGFILGLWALIIMVFFKTYG
Ligand information
Receptor-Ligand Complex Structure
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PDB8imx Structures of substrates- and products-bound glycosylphosphatidylinositol transamidase illuminate GPI-AP biogenesis
Resolution2.85 Å
Binding residue
(original residue number in PDB)		R60 C206 S232 L233 S234 H244
Binding residue
(residue number reindexed from 1)		R20 C166 S192 L193 S194 H204
Enzymatic activity
Enzyme Commision number 3.-.-.-
Gene Ontology
Molecular Function
GO:0003923 GPI-anchor transamidase activity
GO:0008233 peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0008218 bioluminescence
GO:0016255 attachment of GPI anchor to protein
Cellular Component
GO:0042765 GPI-anchor transamidase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8imx, PDBe:8imx, PDBj:8imx
PDBsum8imx
PubMed37684232
UniProtQ92643|GPI8_HUMAN GPI-anchor transamidase (Gene Name=PIGK)

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