Structure of PDB 7z2b Chain K Binding Site BS02

Receptor Information
>7z2b Chain K (length=308) Species: 5821 (Plasmodium berghei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ITYNMNVVIRCRPMSNSEKNEGAKNVIKIMDNKMIVLLKEKRYCFDYVFD
ENSTQEDVYNNSVKPLVDAVIKGYNSTVFAYGATGAGKTHTIIGYKNEPG
IMMMILQDLFKKIKTLKANEYKIKCSFIEIYNENICDLLNPSSEYLDLRE
DPVKGITVSNIFEVCTTSVEEIMELIHTGNRNRTSRSHGVLQVIVEETEK
GQGLYQQTKKGKLCVIDLAGSERGMRMLEGANINRSLLALGNVINALVSR
SKGTSKSNFIPFRDSKLTRLLKDSLGGNCKTLMIANISPSHLSYEDTHNT
LKYANRAK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7z2b Chain K Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7z2b Mechanochemical tuning of a kinesin motor essential for malaria parasite transmission.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		T105 S212
Binding residue
(residue number reindexed from 1)		T89 S185
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7z2b, PDBe:7z2b, PDBj:7z2b
PDBsum7z2b
PubMed36384964
UniProtA0A509AB64

[Back to BioLiP]