Structure of PDB 7u4d Chain K Binding Site BS02

Receptor Information
>7u4d Chain K (length=205) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQ
HLIHLCEEKRASISDAALLDIIYMQFHQHQKVWDVFQMSKGFDMKQFKNS
FKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQ
TPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDSLKAIVFK
QYNQT
Ligand information
>7u4d Chain J (length=139) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gatgtatatatctgacacgtgcctggagactagggagtaatccccttggc
ggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgctagagc
tgtctacgaccaattgagcggcctcggcaccggattctc
Receptor-Ligand Complex Structure
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PDB7u4d CENP-N promotes the compaction of centromeric chromatin.
Resolution8.1 Å
Binding residue
(original residue number in PDB)
K81 M167 R194
Binding residue
(residue number reindexed from 1)
K81 M160 R187
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007059 chromosome segregation
GO:0034080 CENP-A containing chromatin assembly

View graph for
Biological Process
External links
PDB RCSB:7u4d, PDBe:7u4d, PDBj:7u4d
PDBsum7u4d
PubMed35422519
UniProtQ96H22|CENPN_HUMAN Centromere protein N (Gene Name=CENPN)

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