Structure of PDB 7nba Chain K Binding Site BS02

Receptor Information
>7nba Chain K (length=331) Species: 5843 (Plasmodium falciparum NF54) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSCVNIKVIVRCRPLNEKEKNDINNEEVVRINNNEVILTINRNNEIYEKK
YSFDYACDKDVDQKTLFNNYIYQIVDEVLQGFNCTLFCYGQTGTGKTYTM
EGKTGLIFRVTKRIFDILNKRKEEKIMYDFNIKISYLEIYNEELCDLLSS
TMKLRIYEDGLNVDKLEEKSINSFEEIYYIICSAIKKRRTAETAYNKKSS
RSHSIFTITLIIKDINESITKIGKLNLVDLAGSENALKSSSLKIRQQESC
NINQSLLTLGRVINSLIENSSYIPYRDSKLTRLLQDSLGGKTKTFIVATI
SPSSLCIDETLSTLDYVFRAKNIKNRPEINI
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7nba Chain K Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7nba Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		T113 K264 S266
Binding residue
(residue number reindexed from 1)		T97 K198 S200
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:7nba, PDBe:7nba, PDBj:7nba
PDBsum7nba
PubMed34375637
UniProtO77382

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