Structure of PDB 6vz4 Chain K Binding Site BS02

Receptor Information
>6vz4 Chain K (length=616) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKKERNLHLQKINSIIDFIKERQSEQWSRQERCFQFGRLGASLHNQMEKD
EQKRIERTAKQRLAALKSNLLDQTKDTRITQLLRQTNSFLDSLSEAVRAQ
QNDYYEVAHRIKEKIDKQPSILVGGTLKEYQLRGLEWMVSLYNNHLNGIL
ADEMGLGKTIQSISLITYLYEVKKDIGPFLVIVPLSTITNWTLEFEKWAP
SLNTIIYKGTPNQRHSLQHQIRVGNFDVLLTTYEYIIKDKSLLSKHDWAH
MIIDEGHRMKNAQSKLSFTISHYYRTRNRLILTGTPLQNNLPELWALLNF
VLPKIFNSAKTFEDWFNTPFLTEEETLLIIRRLHKVLRPFLLRRLKKEVE
KDLPDKVEKVIKCKLSGLQQQLYQQMLKHNNNKIMQLRKICNHPFVFDEV
EGVVNPSRGNSDLLFRVAGKFELLDRVLPKFKASGHRVLMFFQMTQVMDI
MEDFLRMKDLKYMRLDGSTKTEERTEMLNAFNAPDSDYFCFLLSTRAGGL
GLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTDSVE
EVILERAMQKLDIDGKVIQAGAELDDDELNDTLARSADEKILFDKIDKER
MNQEKEDSEPLGRIRQ
Ligand information
>6vz4 Chain J (length=146) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tcaggatgtatatatctgacacgtgcctggagactagggagtaatcccct
tggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgcta
gagctgtctacgaccaattgagcggcctcggcaccgggattctcga
Receptor-Ligand Complex Structure
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PDB6vz4 Structural insights into assembly and function of the RSC chromatin remodeling complex.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		L528 R557 Y578 K761 M816 G839 R846 S866
Binding residue
(residue number reindexed from 1)		L185 R214 Y235 K389 M444 G467 R474 S494
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0042393 histone binding
GO:0140658 ATP-dependent chromatin remodeler activity

View graph for
Molecular Function
External links
PDB RCSB:6vz4, PDBe:6vz4, PDBj:6vz4
PDBsum6vz4
PubMed33288924
UniProtP32597|STH1_YEAST Nuclear protein STH1/NPS1 (Gene Name=STH1)

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