Structure of PDB 6veq Chain K Binding Site BS02
Receptor Information
>6veq Chain K (length=287) Species:
9606
(Homo sapiens) [
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GEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKL
IMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKEL
GLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDNEE
CGDICNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSEC
LGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDL
HHKQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCP
Ligand information
>6veq Chain L (length=11) Species:
9606
(Homo sapiens) [
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FEDYLHNVVFV
Receptor-Ligand Complex Structure
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PDB
6veq
A structurally minimized yet fully active insulin based on cone-snail venom insulin principles.
Resolution
3.25 Å
Binding residue
(original residue number in PDB)
R14 F88 F89 F96 R118 K121
Binding residue
(residue number reindexed from 1)
R10 F84 F85 F92 R114 K117
Enzymatic activity
Enzyme Commision number
2.7.10.1
: receptor protein-tyrosine kinase.
External links
PDB
RCSB:6veq
,
PDBe:6veq
,
PDBj:6veq
PDBsum
6veq
PubMed
32483339
UniProt
P06213
|INSR_HUMAN Insulin receptor (Gene Name=INSR)
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