Structure of PDB 6s8e Chain K Binding Site BS02

Receptor Information

>6s8e Chain K (length=1023) Species: 930945 (Sulfolobus islandicus REY15A)

FLDYKIIALLHDPPNKAWVITGRARNLTQQLSRKHEKVAKYIINQLFGKN
YSEKVDNADKLASSIDRYLGSIVYKERSLFENRSIFLKNILLSNIQRDIG
NLFPKDKSKLDNLILEYKKLLNVINKTNLILKYQLFYLIYELVWIDSKYE
NTPSDTRNPTHTIFDHLYATAAMMNWILSLEKEAKGYLLGIDTIGVADFI
SKGRKTRDLWISSYLVSALLWYVITWFIEEYGPDVILFPSLRFNQFYAFY
LLEKLRKEGVSEDVIDEIKELITKYIFNGDDLFENLKIPPYPIIPGRITL
ILPGLIREGEEYKKVQDDNCFISKVKERYNEGWRKLIEGLRCYSERKRED
GFWNLVCRVLKLTEDLLQTTPLNIRVKQVSVTEDEIFNNNKLRSDSWKIY
DNKYRQLVSEFKKSKLVKVTPESRLKLFELTKFDKLPQIGEKSKRGYEFC
TSCGVLPAVVIMPKEDELEKKLIDLGIARDEKDVRSIKNMISPGERLCPW
CLVKRALGAEPRLMRILLLGDLYSVEKIVNEIVSRDVKIEIPSTSDIASI
KTFEEMIEKKNEICEDLKEEEVCEKPSESVLSMWQWFNKNYYNGINLTID
PEEYWFSEKRRRYYFSVFRRHRITFPSPYYALVRADSDYLGDLLEGKLTP
YLAGIIDSGDYANISEKKEEVNKLLEEYLVNAGSGSIVDYVKTVLKCIRE
NLNKCSCAEKIYSNEVAKVMFRVNVEKANVEEEVKNSLEYFETILNEGRI
IVTPAWHVSISSALNRGLLVELELVNKHKGFVIYAGGDDLLAMLPVDEVL
DFIKESRRAFAGFGTEKLGNMCLENGFVRINNAYYPSLPIVGRSYSVIIA
HYADPLFFVINDSYNLLEEGKEIIRYRVMYNGEYKDAKKDVAIFRYQGLT
SVIPLSLKRPIVSSVSDFNEIASIIDVILELKKRIDEGRISVSLLYDYEK
YKHLIVASDEKYLTEFLVKDWIKRNSLRKHVEFTIDEKLYGVRLTIENYP
IKIPNDLISNIVYTLRIIYGGEK

Ligand information

• Ligand ID: ZN
• InChI: InChI=1S/Zn/q+2
• InChIKey: PTFCDOFLOPIGGS-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Zn++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Zn+2]
• Formula: Zn
• Name: ZINC ION
• ChEMBL: CHEMBL1236970
• DrugBank: DB14532
• PDB chain: 6s8e Chain K Residue 1101

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6s8e Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
• Resolution: 3.1 Å
• Binding residue (original residue number in PDB): C464 C467 C512
• Binding residue (residue number reindexed from 1): C450 C453 C498
• Annotation score: 4

Gene Ontology

Cellular Component

• GO:0016020 membrane

External links

• PDB: RCSB:6s8e, PDBe:6s8e, PDBj:6s8e
• PDBsum: 6s8e
• PubMed: 32730741
• UniProt: F0NDX2