Structure of PDB 6je4 Chain K Binding Site BS02

Receptor Information
>6je4 Chain K (length=1060) Species: 604162 (Neisseria meningitidis 8013) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAFKPNSINYILGLAIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEV
PKTGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENG
LIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNETADK
ELGALLKGVAGNAHALQTGDFRTPAELALNKFEKESGHIRNQRSDYSHTF
SRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQK
MLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERA
TLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAY
HAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRI
QPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDNT
EEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETARE
VGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRL
YEQQHGKCLYSGKEINLGRLNEKGYVEIDAALPFSRTWDDSFNNKVLVLG
SENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFD
EDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRG
FWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNAHQKTHF
PQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVH
EYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDL
EKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKA
VRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKG
ILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFAS
CHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRP
CRLKKRPPVR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6je4 Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Resolution3.069 Å
Binding residue
(original residue number in PDB)		P52 K53 N944 T946 M947 Y965 H1024 R1033
Binding residue
(residue number reindexed from 1)		P51 K52 N922 T924 M925 Y943 H1002 R1011
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6je4, PDBe:6je4, PDBj:6je4
PDBsum6je4
PubMed31668930
UniProtC9X1G5|CAS9_NEIM8 CRISPR-associated endonuclease Cas9 (Gene Name=cas9)

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