Structure of PDB 6ah3 Chain K Binding Site BS02

Receptor Information

>6ah3 Chain K (length=128) Species: 559292 (Saccharomyces cerevisiae S288C)

NGTLLVPPPRTIANQDHFHRLNYLYQISAYQTRARQKARTDAHTPLARNY
IKSMDLISKKTKTSLLPTIKRTICKKCHRLLWTPKKLEITSDGALSVMCG
CGTVKRFNIGADPNYRTYSEREGNLLNS

Ligand information

>6ah3 Chain T (length=80)

agaagcggauuuagcucaguugggagagcgccagacugaagaucuggagg
uccuguguucgauccacagaauucgcauuu

....<<<<<<<..<<<<........>>>>.<<<<<.......>>>>>...
..<<<<<.......>>>>>>>>>>>>....

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6ah3 Structural insight into precursor tRNA processing by yeast ribonuclease P.
• Resolution: 3.48 Å
• Binding residue (original residue number in PDB): K75 K76 K78
• Binding residue (residue number reindexed from 1): K59 K60 K62

Enzymatic activity

• Enzyme Commision number: 3.1.26.5: ribonuclease P.

Gene Ontology

Molecular Function

• GO:0004526 ribonuclease P activity
• GO:0005515 protein binding
• GO:0008270 zinc ion binding
• GO:0016787 hydrolase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0001682 tRNA 5'-leader removal
• GO:0006396 RNA processing
• GO:0008033 tRNA processing
• GO:0034965 intronic box C/D snoRNA processing

Cellular Component

• GO:0005634 nucleus
• GO:0005655 nucleolar ribonuclease P complex
• GO:1902555 endoribonuclease complex
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6ah3, PDBe:6ah3, PDBj:6ah3
• PDBsum: 6ah3
• PubMed: 30262633
• UniProt: P40571|RPR2_YEAST Ribonuclease P protein subunit RPR2 (Gene Name=RPR2)