Structure of PDB 2wqj Chain K Binding Site BS02

Receptor Information
>2wqj Chain K (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DEDTYYLQVRGRENFEILMKLKESLELMEL
Ligand information
>2wqj Chain L (length=26) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TYYLQVRGRENFEILMKLKESLELME
Receptor-Ligand Complex Structure
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PDB2wqj Structural Evolution of P53, P63, and P73: Implication for Heterotetramer Formation.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		D353 T354 Y355 Y356 L357 Q358 V359 R362 N364 F365 L368 K372 L375 E379
Binding residue
(residue number reindexed from 1)		D3 T4 Y5 Y6 L7 Q8 V9 R12 N14 F15 L18 K22 L25 E29
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
GO:0051262 protein tetramerization
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2wqj, PDBe:2wqj, PDBj:2wqj
PDBsum2wqj
PubMed19815500
UniProtO15350|P73_HUMAN Tumor protein p73 (Gene Name=TP73)

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