Structure of PDB 7aju Chain JP Binding Site BS02

Receptor Information
>7aju Chain JP (length=461) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKIKTIKRSADDYVPVKSTQESQMPRNLNPELHPFERAREYTKALNATKL
ERMFAKPFVGQLGYGHRDGVYAIAKNYGSLNKLATGSADGVIKYWNMSTR
EEFVSFKAHYGLVTGLCVTQPRFHDKKPDLKSQNFMLSCSDDKTVKLWSI
NVDDYSNKNNEEGLIRTFDGESAFQGIDSHRENSTFATGGAKIHLWDVNR
LKPVSDLSWGADNITSLKFNQNETDILASTGSDNSIVLYDLRTNSPTQKI
VQTMRTNAICWNPMEAFNFVTANEDHNAYYYDMRNLSRSLNVFKDHVSAV
MDVDFSPTGDEIVTGSYDKSIRIYKTNHGHSREIYHTKRMQHVFQVKYSM
DSKYIISGSDDGNVRLWRSKAWERSNVKTTREKNKLEYDEKLKERFRHMP
EIKRISRHRHVPQVIKKAQEIKNIELSSIKRREANERRTRKDMPYISERK
KQIVGTVHKYE
Ligand information
>7aju Chain D4 (length=223) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucgacguacuucaaggaucaucuauaggaaucgucacucuuugacucuu
cccacugaauccaacuugguugaugagucccauaaccuuuguaccccaga
gugagaaauagcuugguccgcaauccuuagcgguucggccaucuauaauu
uugaauaaaaauuuugccguugcuauggcgcgaugaucacccaugggugg
guacaaauggcagucugacaagu
..................................................
.............<<<<<.................<<<<<<<<<<<....
<........<<..<<<.<<<.<<<<......>>>>>>>>>>.>>..<<<<
<<....>>>.>>>..<<<<<....>>>>>........><<<<..>>>>>>
>>>>>>>.>>........>>>>>
Receptor-Ligand Complex Structure
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PDB7aju Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		S18 E21 R52 M53 F54 K56 P57 F58 E341 H344 T345 K346 R347 R373 R382 T387 R389 E390 K393 L394 H418
Binding residue
(residue number reindexed from 1)		S18 E21 R52 M53 F54 K56 P57 F58 E333 H336 T337 K338 R339 R365 R374 T379 R381 E382 K385 L386 H410
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7aju, PDBe:7aju, PDBj:7aju
PDBsum7aju
PubMed33326748
UniProtP33750|DCA13_YEAST Protein SOF1 (Gene Name=SOF1)

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