Structure of PDB 6zqg Chain JD Binding Site BS02

Receptor Information
>6zqg Chain JD (length=829) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GTYRKRFNEKARSGHMAKLKELKRIRNKQFTRSKVSRLKKKRLDKFIEHQ
LKREERKTIIGKLQDYKVEVSRSDEIQKARIQLPVFGEEHKIMEAIHHND
VVIICGETGSGKTTQVPQFLYEAGFGAEDSPDYPGMVGITQPRRVAAVSM
AERVANELGDHGHKVGYQIRFDSTAKEDTKVKFMTDGVLLREMMHDFKLT
KYSSIIIDEAHERNINTDILIGMLSRCVRLRAKLHKENPIEHKKLKLIIM
SATLRVSDFSENKTLFPIAPPVLQVDARQFPVSIHFNRRTAFNYTDEAFR
KTCKIHQKLPPGAILVFLTGQQEITHMVKRLRKEFPFKKNANDPLYVLPL
YSLLPTKEQMRVFQKPPQGSRLCIVATNVAETSLTIPGVRYVVDSGRSKE
RKYNESNGVQSFEVGWVSKASANQRSGRAGRTGPGHCYRLYSSAVFEHDF
EQFSKPEILRMPVESIVLQMKSMAIHNIINFPFPTPPDRVALSKAIQLLQ
YLGALDNKEMITEDGKKMSLFPLSPRFSKMLLVSDEKACLPYIVAIVSAL
SVGDPFINEFELGGMDPELKKELRSKFYKSRSQFSKLDKFSDVFRLLSVV
SAMDYVPKEQKEIFMKKNFLRGKLMEEIVKLRKQLMYIIKSNTSKENIAV
VIRNEDLKSDIPSVIQIKLLKQMICAGFVDHVAVRAIPYIPVLATRTPNI
EDCFVYIHPTSILNNLGEMPPKYMLYYSLHLGGNNKTRMNTLCDIASTPL
ANIARKGLLLTYSKPLTGQGLKTVNLSPTERYCYVVPRFGSKIGWDLNPI
AVHQKKQKGQWTVIKFITRKGFQTITGEE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zqg 90 S pre-ribosome transformation into the primordial 40 S subunit.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		R478 G495 V496 T627 G628 Q629 S736 K783 E784 R785 P906 P1137
Binding residue
(residue number reindexed from 1)		R170 G187 V188 T319 G320 Q321 S352 K399 E400 R401 P522 P709
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008186 ATP-dependent activity, acting on RNA
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0022613 ribonucleoprotein complex biogenesis
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zqg, PDBe:6zqg, PDBj:6zqg
PDBsum6zqg
PubMed32943521
UniProtQ04217|DHR1_YEAST Probable ATP-dependent RNA helicase DHR1 (Gene Name=ECM16)

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