Structure of PDB 6hcf Chain J3 Binding Site BS02

Receptor Information

>6hcf Chain J3 (length=170) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTV
RSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGF
GIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRI
SKEEAMRWFQQKYDGIILPG

Ligand information

>6hcf Chain 72 (length=120) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gucuacggccauaccacccugaacgcgcccgaucucgucugaucucggaa
gcuaagcagggucgggccugguuaguacuuggaugggagaccgccuggga
auaccgggugcuguaggcuu

....<.<<.....<<<<<<<<.....<<<<<..............>>>..
>>....>>>>>>.>><<<<<<<......<.<<..<<....>>.>>.>...
..>>>>>>>.>>.>......

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6hcf ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Resolution	3.9 Å
Binding residue (original residue number in PDB)	N10 M12 Q46 T47 V49 C72 R75 K144 C150 I151 K154
Binding residue (residue number reindexed from 1)	N3 M5 Q39 T40 V42 C65 R68 K137 C143 I144 K147

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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External links

PDB	RCSB:6hcf, PDBe:6hcf, PDBj:6hcf
PDBsum	6hcf
PubMed	30293783
UniProt	G1TUB8\|RL11_RABIT Large ribosomal subunit protein uL5 (Gene Name=RPL11)

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