Structure of PDB 7r81 Chain J1 Binding Site BS02

Receptor Information

>7r81 Chain J1 (length=236) Species: 5141 (Neurospora crassa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NPLIEKRPRNFGIGQAIQPKRNLSRMVKWPEYVRLQRQKKILNMRLKVPP
ALAQFQQVLDKNTAAQAFKLLNKYRPETKTEKKERLLQEATAIKEGKKKE
DVSKKPYVVKYGLNHVVGLIENKKASLVLIPNDVDPIELVVFLPALCRKM
GIPYAIIKGKARLGTVVHKKTAAVLALTEVRAEDKNELAKLVSAIKEGYL
EKNEQARRQWGGGIMGVKSQMKIAKRKKALENAIKV

Ligand information

>7r81 Chain C1 (length=158) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

aaacuuucaacaacggaucucuugguucuggcaucgaugaagaacgcagc
gaaaugcgauagguaaugugaauugcagaauucagugaaucaucgaaucu
uugaacgcacauugcgcucgccaguauucuggcgagcaugccuguucgag
cgucauuu

.........................................<<<<<<<<<
....>>>>.....<.<<<......>>..............>>>..>...>
>>....<<.....>><<<<<<<<<....>>>>>>>>>.............
........

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7r81 Structure of the translating Neurospora ribosome arrested by cycloheximide
Resolution	2.7 Å
Binding residue (original residue number in PDB)	Y58 V59 Q62 R63 K66 K87 K184 R188
Binding residue (residue number reindexed from 1)	Y32 V33 Q36 R37 K40 K61 K158 R162

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding

	Biological Process
GO:0000470	maturation of LSU-rRNA
GO:0042254	ribosome biogenesis

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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External links

PDB	RCSB:7r81, PDBe:7r81, PDBj:7r81
PDBsum	7r81
PubMed	34815343
UniProt	Q6MFL6

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