Structure of PDB 8srp Chain J Binding Site BS02

Receptor Information
>8srp Chain J (length=84) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDYFKYHNMRPPFTYATLIRWAILEAPERQRTLNEIYHWFTRMFAYFRNH
PATWKNAIRHNLSLHKCFVRVESEKGAVWTVDEF
Ligand information
>8srp Chain M (length=54) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ttgtttgtttgtttgtttgtttgtttgtttgtttgtttgtttgtttgttt
gttt
Receptor-Ligand Complex Structure
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PDB8srp FoxP3 forms Ladder-like multimer to bridge TTTG repeats
Resolution3.7 Å
Binding residue
(original residue number in PDB)
L360 R386 S390
Binding residue
(residue number reindexed from 1)
L33 R59 S63
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:8srp, PDBe:8srp, PDBj:8srp
PDBsum8srp
PubMed38030726
UniProtQ99JB6|FOXP3_MOUSE Forkhead box protein P3 (Gene Name=Foxp3)

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