Structure of PDB 8siy Chain J Binding Site BS02

Receptor Information
>8siy Chain J (length=93) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLA
HYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA
Ligand information
>8siy Chain L (length=147) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aggatgtatatatctgacacgtgcctggagactagggagtaatccccttg
gcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgctaga
gctgtctacgaccaattgagcggcctcggcaccgggattctccagga
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8siy A dual role for the chromatin reader ORCA/LRWD1 in targeting the origin recognition complex to chromatin.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		T32 Y42 G53 I54 S56 S87 T88
Binding residue
(residue number reindexed from 1)		T1 Y11 G22 I23 S25 S56 T57
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8siy, PDBe:8siy, PDBj:8siy
PDBsum8siy
PubMed37551430
UniProtP02281|H2B11_XENLA Histone H2B 1.1

[Back to BioLiP]